CXCR5- CD19low seemed to be related to plasmacytosis as suggested by the correlation with PB frequencies. Our data suggest that CXCR5-CD19low B cells are precursors of PBs and targeting this subset in SLE may have therapeutic value. References Odendahl M, Jacobi A, Hansen A, Feist E, H...
Compared with never cGVHD controls, patients with later cGVHD had significantly higher CD19+CD21low B cells (23.5% versus 15.2%, P = .004, Figure 1), CD4+ T cells (394 versus 127 × 106/L, P < .001), CD4+CD45RA+ naïve T cells (28.7% versus 16.3%, P < .001), and CD4+...
IV期组的CD4^+CD25^+highCDl27^Low,CDl9^+,CDl9^+CD23^+表达量明显高于O-II期组;CD4^+CD25^+highCDl27^Low,CDl9^+CD23^+有明显的正相关性.结论B—CLL患者外周血中CD4^+CD25^+highCD127^Low的表达量增高,与CD19^+,CD19^+CD23^+的表达量增高明显相关,可能是B—CLL患者CD19^+CD23^+克隆性...
These results suggest that CD19(-)CD45(low/-) fully differentiated plasma cells enrich for long-lived and tumor-initiating cells whereas B cells or plasmablasts do not. 展开 关键词: multiple myeloma myeloma-initiating cells xenotransplantation ...
CD19(+)CD38(low) or CD138(+)CD38(+) B-lineage cells in human bone grafts; and these grafts were clonally derived from patient myeloma cells. Meanwhile, CD19(+)CD38(low) xenografts were detected in human bone-bearing mice transplanted with CD19(+)CD38(low/-) B cells from 8 of 22 ...
Over 80% of CD21hi B-cells were also positive for IgD and HLA-DR (Table 2). Based on these data, we characterize rhesus macaque MZ B-cells as CD19+, CD20+, CD21hi, IgM+, CD22+, CD38+, BTLA+, CD40+, CCR6+ and BCL-2+ with some variation in expression of IgD and HLA-DR...
CD81encodes a surface glycoprotein known as tetraspin which is essential for clonal expansion of B cells and antibody production. Defects in this gene are associated with common variable immunodeficiency 6 (CVID6)21. ICOSplays a significant role in cell–cell interaction, immune responses and effic...
Phenotypic characteristics of B cells in Behet's disease: increased activity in B cell subsets. RESULTS: Although the B cell number (CD19+) was normal, CD13 and CD33 positive B cells were more numerous in BD and sepsis compared to healthy ... E Ekşioglu-Demiralp,A Kibaroglu,H Diresk...
L stimulation.We revealed an increase in the levels of circulating total plasmablasts, plasma cells and mature-naive B cells and a decrease in the levels of germinal centre-like B cells and CD19<sup>+</sup>IgG<sup>+</sup> B cells in PNS. In addition, although the expression of CD86 ...
In addition, CD19 + B cells were generated from the graft-derived cells isolated from aorta–gonad–mesonephros (AGM) regions of the YS–YS chimeras; however, the frequency of the YS-derived B cell was low (1.0 ± 0.6%) when co-cultured with OP9 stromal cells. These results demonstrate...