B will also afford excellent recovery of high-purity, viable cells for use in downstream molecular studies; for example, those in which cells are to be lysed while still attached to beads, and nucleic acids or proteins further purified. Note that intact cells will not be released from these ...
急性B淋巴细胞白血病(B-ALL)是急性淋巴细胞白血病最常见的类型,目前治疗以化疗为主,但具有严重的不良反应。CD19普遍在B系恶性肿瘤中高表达,并在B细胞信号转导、活化以及发育等过程起关键作用,成为B细胞恶性肿瘤治疗的有效靶点之一。目前开发了多种靶向CD19的疗法,包括抗体药物偶联物、单克隆抗体、双特异性抗体和嵌合...
B cells isolated with Dynabeads CD19 and released with DETACHaBEAD CD19 are pure, viable, phenotypically unaltered and unactivated. Cells are suitable for applications such as further sorting, culturing studies and flow cytometry.
The monoclonal blood CD19+ cells are not eliminated by any of the chemotherapy regimens analyzed and remain at high levels during transient remissions. Patients in the progressive phase of disease or in relapse have significantly higher numbers of B cells than do patients in transient remission or...
方法1例难治B-ALL患者,CD19 CAR-T(鼠源,克隆号:FMC63)细胞治疗后桥接同胞全相合异基因造血干细胞移植,后再次复发。接受CD19 CAR-T(可变区人源化的FMC63)细胞治疗再次缓解,缓解后先后接受单独输注供者造血干细胞、供者T淋巴细胞的维持治疗,期间监测患者细胞因子水平、CD19 CAR-T细胞比例、CD19 CAR的DNA表达...
CD9-BV4324bHEK293Biotinylated FMC63 scFv, Fc,Avitag™(MALS verified) MBS-C008ActiveMax® Anti-FMC63 Antibody μBeads, premium grade (for cells) FM3-PFM721HEK293PE-Labeled Monoclonal Anti-FMC63 Antibody, Rabbit IgG (1G10) (0.03% Proclin) ...
Dynabeads® CD19 Pan B Dynabeads® CD19 Pan B are superparamagnetic beads covalently coupled with an anti-human CD19 antibody that enable easy isolation or depletion of human CD19+ B cells directly from whole blood, bone marrow, buffy coat, mononuclear cells (MNC), and tissue digests. ...
CD19 belongs to immunoglobulin superfamily and is a part of multimolecular complex called B cell co-receptor [64]. High expression of CD19 on one subpopulations of circulating B cells were shown in SLE patients and ANCA-associated vasculitis; these B cells are precursors of pre-plasmablasts; ...
货号:ABC-1154 价格:¥询价 规格: 1 vial 数量:-+ 产品描述 参考文献 资料下载 相关产品 产品描述/Products Description Mouse spleen is dissociated into a single cell suspension. The splenocytes are enriched by density separation. CD4+ T cells, CD8+T Cells, and CD19+ B Cells are isolated us...
Late (persisting, M7–M60) CAR-T cells are in green hues; mid (M4–6) CAR-T cells are in black/blue hues; and early (M1–3) CAR-T cells are in pink/red hues. b, Stacked bar plots show dynamic cell type proportions over time for a representative patient (P01). The top five ...