Low Serum Alpha-1 Antitrypsin (AAT) in Family Members of Individuals with Autism Correlates with PiMZ Genotype.AimDeficiency of Alpha-1-antitrypsin (AAT) can be a genetic condition that increases the risk of developing liver, lung and... AJ Russo,L Neville,C Wroge - 《Biomarker Insights》 ...
The aim of this study was to examine oxidative stress and low level of alpha-1-antitrypsin (A1AT) in primary Sjgren's syndrome (pSS), and evaluate the associated autoreactivity against unmodified and their 4-hydroxy-2-nonenal (HNE)-modified peptides with pSS. Two differentially expressed ...
It has recently been shown that () and its ligand alpha(1) (alpha(1)PI; alpha(1)antitrypsin) act as fusion cofactors. The present study shows that decreased infectivity is significantly correlated with decreased density of but not with decreased nor chemokine receptors. In vitro infectivity ...
Alpha-1-antitrypsin, S100A9 and gastric intrinsic factor have been proposed as biomarkers in gastric fluid (Hsu et al, 2007; Wu et al, 2012), whereas alpha-defensins (Kim et al, 2010) and Cathepsin B (Ebert et al, 2005a) have been identified from tissue analysis. Other recently ...
Differential recognition of alpha 1-antitrypsin-elastase and alpha 1-antichymotrypsin-cathepsin-G complexes by the low density lipoprotein receptor- related protein. J Biol Chem. 1995;270:2841-2845.Poller, W., Willnow, T. E., Hilpert, J. & Herz, J. (1995)Differential recognition of alpha 1...
Lman1 −/− mice exhibit ER accumulation of another LMAN1 cargo, alpha-1 antitrypsin (A1AT), with an intermediate level of A1AT ER retention observed in Lman1 cgt/cgt mice. Finally, the previously reported strain-specific, partially penetrant, perinatal lethality of LMAN1-deficient mice (...
The structural determinants of the unusually low pK(a) values of Cys282 in human creatine kinase and Cys232 in alpha1-antitrypsin were studied computationa... MM Naor,JH Jensen - 《Proteins Structure Function & Bioinformatics》 被引量: 66发表: 2004年 Site-specific modification of rabbit muscle...
Discontinuing GLP-1 RA use before endoscopy may not be necessary; general anesthesia could mitigate high-risk complications. SHOW MORE Braden Kuo, MD, explains how GLP-1 RA use increases residual gastric content but does not significantly impact negative endoscopy outcomes. ...
Alpha-1-antitrypsin A1AT_HUMAN 5.37 46,878 1031 60 Ig gamma-3 chain C region IGHG3_HUMAN 8.23 42,287 249 34 Alpha-2-HS-glycoprotein FETUA_HUMAN 5.43 40,098 209 13 Kininogen-1 KNG1_HUMAN 6.34 72,996 143 11 Beta-2-glycoprotein 1 APOH_HUMAN 8.34 39,584 177 29 Ig gamma-4 chain C...
Specifically, Human 7 removes high abundant proteins by binding albumin, IgG, IgA, transferrin, haptoglobin, and antitrypsin, whereas Human 14 removes the high and intermediate abundant proteins by binding the six proteins indicated above plus alpha-2-macroglobulin, alpha-1-acid glycoprotein, IgM, ...