Additional studies are needed to determine the long-term health effects of obesity medications in large and diverse patient populations. Section Editor: Mary McGrae McDermott, MD, Senior Editor. Submissions:We encourage authors to submit papers for consideration as a Review. Please contact Mary McG...
Cushing's disease represents a unique model for investigating effects of prolonged hypercortisolism on the human brain. Earlier studies using Cushing's disease to investigate the long-term effects of hypercortisolism on the structure of the brain showed smaller gray matter volumes of the ACC, ...
effects on neurodevelopment, the child's broader environment, genetic makeup, and parental behaviors play equally critical roles in shaping long-term outcomes.63, 64, 65 Key factors influencing development include genetic predispositions, the impact of environmental stressors, and epigenetic changes that...
The last experiment assessed the effects of a PDTC administration 1 h after PSS on behavioral responses and hippocampal expression of p50, p65, I-kBa, p38, and phospho-p38. Neuropsychopharmacology 2288 NF-jB complex in an animal model of PTSD H Cohen et al Figure 1 The cutoff behavioral ...
What happens if trauma is left untreated? Unaddressed trauma can have serious—even devastating—effects on relationships, career, and day-to-day functioning. Post-Traumatic Stress Disorder (PTSD) can lead people to distrust or lash out at others, making it difficult to maintain intimate relationshi...
The neuropeptide oxytocin has been implicated in the infant response to maternal care and is therefore another potential candidate for mediating the long-term effects of early adversity on the adult brain (Bales and Perkeybile, 2012). While a role for the oxytocin system has been extensively studi...
There is limited data on its related effects in humans and even less on its long-term application. In this multi-center cross-sectional study from the International Group for the Study of Lithium-treated Patients (IGSLi), we compared three groups: bipolar patients without long-term lithium ...
Burnout: The Culmination Of Long-Term Stress 来自 EBSCO 喜欢 0 阅读量: 13 作者: Hunsaker, Johanna S 摘要: Focuses on the management of job stress. Assessment of lifestyle and values clarification; Control of energy expenditure patterns; Increase of capital in employee training. 被引量: 6 ...
The BLA mediates emotional memories, and long-term potentiation (LTP) is widely considered a trace of memory. We identified that the cholecystokinin knockout (CCK-KO) mice impaired LTP in the BLA, while the application of CCK4 induced LTP after low-frequency stimulation (LFS). The entorhinal ...
Their needs go beyond stump maintenance—self image, PTSD, retraining for a career, and living with a lifelong disability will be essential components of the long-term care. In addition, there are numerous potential toxic and infectious exposures our troops face that are uncommon in the U.S....