Abstract Importance An understanding of the long-term outcomes of patients with advanced chronic kidney disease not treated with maintenance dialysis is needed to improve shared decision-making and care practices for this population. Objective To evaluate survival, use of health care resources, changes ...
One-Year Weight Change in Studies Included in Systematic Review for Long-Term Pharmacotherapy of Obesitya View LargeDownload Podcast (6:43) Long-term Drug Treatment for Obesity: A Systematic and Clinical Review 1x 0:00 / 0:00 Supplement. eTable. Interactions, Contraindications, and Cautions and...
In 1875, symptoms that constitute the condition now known as NAS were first recognized under the term Congenital Morphinism in Germany.7,16 At that time, it was mistakenly believed that opioid use in pregnant women had no impact on their newborns, as morphine was associated with female sterilit...
There is no shame in re-experiencing PTSD symptoms nor in returning to therapy when such relapses occur; indeed, many forms of trauma therapy explicitly encourage periodic “maintenance sessions” to reinforce coping skills and ensure that symptoms stay manageable. ...
et al. Cholecystokinin B receptor antagonists for the treatment of depression via blocking long-term potentiation in the basolateral amygdala. Mol Psychiatry 28, 3459–3474 (2023). https://doi.org/10.1038/s41380-023-02127-7 Download citation Received12 June 2022 Revised01 June 2023 Accepted13 ...
The majority of these symptoms are also seen in stress-related psychiatric disorders, suggesting a common underlying mechanism. After successful biochemical treatment of Cushing's disease, psychiatric symptoms decrease, but patients still show cogni- tive impairment (Dorn and Cerrone, 2000; Forget et ...
Besides GR and associated HPA axis dysregulation, neurotrophins such as BDNF have been implicated in the short- and long-term effects of CT. BDNF is involved in important neurodevelopmental processes, such as the differentiation and growth of neurons, and its expression can be modified by life exp...
There is evidence of differences in the brain’s structure between bipolar patients and healthy individuals, as well as changes over time in patients. Lithium constitutes the gold standard in long-term prophylactic treatment. Appropriate therapy that prevents new episodes improves the disease’s course...
Co-occurring disorders are sometimes difficult to diagnose, largely due to the symptoms often being complex and varying in severity. Consequently, most often patients end up receiving treatment for one disorder while the other continues to go untreated. ...
A comprehensive physical examination can help the HCP, given many biomedical exposures or injuries, such as TBI, present with symptoms similar to psychiatric illnesses like PTSD. Patients may have both—yet each require highly specialized care and long-term follow-up. Civilian medical resources are ...