Interestingly, the centromeric breakpoint is located in intron 4 of thegene (pipecolic acid oxidase; NM_016518) and the telomeric breakpoint in intron 5 of thegene (gametogenetin binding protein 2; NM_024835) c
a long poly-pyrimidine tract on intron 21 may predispose to triplex DNA formation and recombination. Third, the presence of several homologous genes with high sequence similarity may predispose it to mutations from gene conversion. Thus, the locus effect coupled with the two-hit mechanism of cysto...
Efforts to manipulate locus-specific histone acetylation to assess their causal role in gene expression and cellular and behavioural phenotypes have been impeded by a lack of experimental tools. The Cas9 nuclease has been adapted to target epigenomic modifications, but a detailed description of the pa...
On chromosome 5, the peak LOD score occurred in the 5q33-5ter region, near the FXII gene. Addition of a 46C/T mutation in the FXII gene increased the multipoint LOD score to 10.21 (P=3.6×10−12). A bivariate linkage analysis of FXII activity and thrombosis further improved the ...
In this study, we investigated the immunoglobulin heavy (IGH) gene locus of torafugu (Takifugu rubripes) from publicly available assembly sequences and presented an annotated locus map, including the IGHV genes, pseudogenes, and IGHC genes. Three new IGHV gene families (IGHV3-IGHV5) were discov...
Mathematics The set or configuration of all points whose coordinates satisfy a single equation or one or more algebraic conditions.3.【数学】 轨迹：其坐标满足某一等式或一个或多个代数条件的所有的点的集合或组合 4.The position that a given gene occupies on a chromosome.基因座：在一条...
We have previously reported the nucleotide sequence of the Streptococcus pneumoniae type 19F capsular polysaccharide synthesis locus (cps19f), which consis... J,K,Morona,... - 《Journal of Bacteriology》 被引量: 62发表: 1997年 Molecular structure of the gene cluster responsible for the synthesis...
Flowering is an important process in higher plants and is regulated by a variety of factors, including light, temperature, and phytohormones. Flowering restriction has a considerable impact on the commodity value and production cost of many horticultural crops. In Arabidopsis, the FT/TFL1 gene famil...
and alignments are compared to a list of authentically expressed L1 loci from a bulk RNA-Seq dataset in a matched sample (2). Reads are aligned using 10x Genomics and gene expression is quantified using Seurat (3).B. A table showing the number of cells captured per dataset, the average ...
Uzbekova. Alteration of energy metabolism gene expression in cumulus cells affects oocyte maturation via MOS-mitogen-activated protein kinase pathway in dairy ... D Brisard,A Desmarchais,JL Touzé,... - 《Theriogenology》 被引量: 17发表: 2014年 Alteration of energy metabolism gene expression in...