lncRNAMIAT facilitates the differentiation of adiposederived mesenchymal stem cells into lymphatic endothelial cells via the miR495/Prox1 axislymphedemalong non-coding RNA myocardial infarction associated transcriptadipose derived mesenchymal stem cells
一致地,RGMB-AS1过表达组小鼠肿瘤中HMOX1的蛋白水平增加(图2D)。使用shRNA在RGMB-AS1过表达稳定细胞中敲低HMOX1,导致细胞活力和克隆形成能力增加(图2E和F)。与细胞结果一致,裸鼠体内实验也显示,使用shRNA敲低HMOX1削弱了RGMB-AS1过表达对肿瘤进展的影响(图2G-I)。然后我们调查RGMB-AS1如何调节HMOX1蛋白水平。CH...
LNCRNA MIRT1: A CRITICAL REGULATORY FACTOR IN CHRONIC INTERMITTENT HYPOXIA EXAGGERATED POST-MI CARDIAC REMODELINGdoi:10.1016/S0735-1097(22)02008-3Zexuan LiYunhui DuXiao WangShaoping NieElsevier BVJournal of the American College of Cardiology
Oxygen–glucose deprivationBrain microvascular endothelial cells injuryRmstmiR-150EGb761In the present study, we aimed to illustrate the roles and working mechanisms of long non-coding RNA (lncRNA) rhabdomyosarcoma 2-associated transcript (Rmst) and EGb761 in oxygen–glucose deprivation (OGD)-...
LncRNA XIST sponged miR-182-5p which targeted IGF-1R. MiR-182-5p mimic reversed the above effects of lncRNA XIST overexpression on IR cells. Conclusions In conclusion, lncRNA XIST/miR-182-5p axis alleviates hepatic IR in vitro via IGF-1R/PI3K/Akt signaling pathway, which could be the ...
lncRNA RMRPmiR-1-5psepsisBoth long non-coding RNA (lncRNA) RMRP and heat shock protein (HSP) 70 have been known to play crucial roles in inflammation. The present study investigated the roles of lncRNA RMRP and HSP70 protein 4 (HSPA4) in lipopolysaccharide (LPS)-induced sepsis. The C57...
Systematic Analysis of the Expression and Prognostic Significance of P4HA1 in Pancreatic Cancer and Construction of a lncRNA-miRNA-P4HA1 Regulatory Axis.doi:10.1155/2020/8877334Zhili HuFang SongYangzhi HuTianyou LiaoHindawi Limited
lncRNA HOTAIR upregulates COX-2 expression to promote invasion and migration of nasopharyngeal carcinoma by interacting with miR-101Nasopharyngeal carcinomaTumorigenesis and progressionHOTAlRmiR-101COX-2Nasopharyngeal carcinoma (NPC) is the most common type of head and neck cancers which is notable for...
LncRNA EGFRAS1 promotes lung cancer cell proliferation, invasion and metastasis via regulation of miR449a/HDAC1doi:10.3892/etm.2024.12777COMPETITIVE endogenous RNALINCRNANON-small-cell lung carcinomaCANCER cell proliferationHISTONE deacetylaseThere is increasing evidence that long non-coding (l...
Here, we identified a novel cancer-related lncRNA, termed lncRNA GCMA (Gastric Cancer metastasis-associated lncRNA), which was upregulated in GC tissues with lymph node metastasis (LNM) compared with tissues without LNM. High expression of GCMA was significantly associated with poor prognosis of...