Tait BD. The ever-expanding list of HLA alleles: changing HLA nomenclature and its relevance to clinical transplantation. Transplant Rev (Orlando). 2011;25(1):1–8. :10.1016/j.trre.2010.08.001. Epub 2010 Oct 27.Tait, B.D. (2011) The ever expanding list of HLA alleles: changing HLA ...
seq2HLAseq2HLAis an annotation tool for obtaining an individual's HLA class I and II type and expression using standard NGS RNA-Seq data infastqformat. It comprises mapping RNA-Seq reads against a reference database of HLA alleles usingbowtie, determining and reporting HLA type, confidence sc...
Doublet identification by modeling alleles from beta-binomial distribution. Outperforms vireo and scSplit in simulated and experimental data. Paper Heaton, Haynes. “Souporcell: Robust Clustering of Single-Cell RNA-Seq Data by Genotype without Reference Genotypes.” Nature MethOds 17 (2020). ...
Co-Operative Additive Effects between HLA Alleles in Control of HIV-1 P. Matthews,Jennifer Listgarten, J. Carlson, R. Payne, KH Huang, J Frater, D Goedhals, D Steyn, D van Vuuren, P Paioni, P Jooste, A Ogwu, R Shapiro, Z Mncube, T Ndung'u, B Walker, D Heckerman, P Goulder...
Risk alleles on chromosome 15q25 were shown to modulate the mRNA expression levels of the CHRNA5 gene in the brain33,34 and lung35 tissues as well as the expression of CHRNA5 and IREB2 genes in sputum.36 The regulation of genes in primary disease tissues, such as lung and sputum, ...
- 《Portuguese Journal of Nephrology & Hypertension》 被引量: 4发表: 2016年 Baseline Data and HLA Alleles and Haplotypes Diversity and Panel Reactive Antibody in Kidney Transplant Candidates in Southwest China Background: To investigate the baseline data characteristic, human leukocyte antigen (HLA) ...
1 when he hypothesized that infiltration of enlarged cells in a spleen represented a “neoplasm.” The biochemical basis for the disease was elucidated 83 years later (1965) by Roscoe Brady\"s group at the National Institutes of Health.2 The molecular basis of the disease was elucidated in ...
The number of known HLA alleles is constantly and exponentially growing resulting in HLA typing ambiguities, which need to be resolved. Knowing the allele frequency categorized in common, well-documented and rare as achieved in the common and well-documented (CWD) allele lists may help in the ...
Increasing evidence suggests that HLA alleles are strongly associated with drug-induced-CIDRs. The pathomechanisms for CIDRs include genetic polymorphisms affecting complex immune-specific HLA/drug antigen/T-cell receptor interactions and drug metabolism. Pharmacogenomic tests to prevent CIDRs have been ...
Most HLA alleles described in the IMGT/HLA database are very rare. The Common and Well Documented (CWD) allele list was created in 2007 to identify the subset of HLA alleles likely to be observed again, and the CWD list was revised in 2013 (CWD2). Our aim was to identify which ...