The present invention provides liposome-containing drug administration carriers that have improved residence time in the blood and improved migration into tumor cells as compared with conventional ones and that have reduced accumulation in the heart, and a pharmaceutical composition for treating a cancer ...
Cancer cell membrane-decorated hybrid liposomes for treating metastatic breast cancer based on enhanced cancer immunotherapy 来自 Springer 喜欢 0 阅读量: 7 作者:J Lee,WT Lee,TL Xuan,SY Yu 摘要: Our goal was to increase the targetability of our nanoparticles to specific targets to increase their...
The invention also provides methods of treating hyperproliferative disorders by targeting hyperproliferative disease cells for the targeted delivery of a therapeutic or diagnostic agent.马里亚·波利坎德里图·兰布罗斯黄英
The utilization of stem cells as novel carriers to target tissues or organs of interest is a challenging task in delivery system. The composite cellular delivery with diverse signalling molecules as therapeutics increases stem cell capability and possesses the promising potential to augment, modify or ...
In further studies on Lipo-PTO for treating breast cancer (BC) in mouse models, Lipo-PTO usage was characterized by a high degree of biocompatibility, optimal retention time pharmacokinetics and tumour regression with minimal collateral damages. This study here thus illustrates an innovative strategy ...
Introduction Cancer drug resistance is referring to the tolerance of cancer cells when treated withchemotherapy.Once the drug resistance occurs,therapeutic effect of anticancer drugwould decrease significantly.Multi-drug resistance can be explained as a condition thatonce cancer cells became resistant to on...
Rudra et al Dovepress Cancer is a disease that is notoriously difficult to treat.4 Cytotoxic drugs involved in treatment are designed to kill tumor cells, but generally also display unwanted toxicities as they lack tumor cell selectivity.5 Liposomes, as carriers for anticancer drugs, have been...
Optimizing liposomes delivering arsenic trioxide to cervical cancer cells in vitroArsenic trioxide (ATO) has been demonstrated to have significant therapeutic effects against acute promyelocytic leukemia and various haematological malignancies. However the lack of success in clinical trials in treating solid ...
27. A method for treating cancer, the method comprising: identifying a subject having cancer; and administering a therapeutically effective amount of a composition comprising: a crosslinked multilamellar liposome having an exterior surface and an interior surface, the interior surface defining a central...
We actually observed that ILD possesses therapeutic efficacy against DXR-insensitive stomach cancer cells, which express a multidrug resistance gene (data not shown). This property would have special importance in treating gastrointestinal cancers clinically, as they often show drug resistance against many...