increase drug solubility, reduce drug toxicity, improve targeted drug release, etc. Thus, in first aspect the invention provides liposomes that are useful for delivery of bioactive agents such as therapeutics. Among others, the liposomes of the invention are capable of delivering their payload at ...
Liposomes in Drug Delivery Summary Liposomes (phospholipid-based vesicles) have been investigated since 1970 as a system for the delivery or targeting of drugs to specific sites in the body. Because of their structural versatility in terms of size, composisition, surface charge, bilayer fluidity an...
Liposomes (phospholipid vesicles) have been investigated as a means of achieving such selectivity and of prolonging the duration of drug activity. With reference to current and future clinical applications, this article outlines why liposomes are appropriate vehicles for drug delivery and describes the ...
In the past decade, liposomal formulations have been extensively employed to enhance the efficiency of drug delivery via several routes of administration. In a number of instances, liposomal drug formulations have been shown to be markedly superior to conventional dosage forms, especially for ...
Intravitreal administration of drugs has raised a large interest during the last two decades improving the treatment of infectious diseases of the posterior segment of the eye or edematous maculopathies. This route of administration allows achieving high drug concentrations in the vitreous and avoiding...
While the granuloma is critical for protection against disease, it can also act as a double-edged sword.[25]On the one hand, it isolates infectious organisms, preventing dissemination to peripheral organs; yet on the other hand, within these cellular aggregates, the bacilli do not replicate but...
This includes long-circulating liposomes, stimuli-responsive liposomes, nebulized liposomes, elastic liposomes for topical, oral and transdermal delivery and ... Claudia,Zylberberg,Sandro,... - 《Drug Delivery》 被引量: 19发表: 2016年 Stimulus-responsive liposomes as smart nanoplatforms for drug deli...
Liposomes for drug delivery and methods for their preparation A liposome comprising * 25% to 45% (mol / mol) of anionic lipid, * less than 10% cholesterol (mol / mol) and * a therapeutic agent selected from the group ... SA Petersen,AF Vikbjerg,K Joergensen,... 被引量: 0发表: 20...
Designed Self Assembly of Nano-Liposomes in the Male Reproductive Tract for Model Drug Delivery to the Prostate The Open Nanoscience JournalGuha, S.K.; Chauhan, V.; Banerjee, S. Designed self assembly of nano-liposomes in the male reproductive tract for model drug delivery to the prostate. Op...
Liposomes were first proposed and tested as a drug delivery system 25 years ago. Since then, advances in our understanding of the face and behaviour of liposomes at the cellular and subcellular level in vivo have allowed the rational design of constructs for use in the treatment and prevention ...