Liposomes provide an extremely flexible drug carrier modality with many potential applications and an impressive track record as a carrier system. The ultimate goal of a liposome formulation is to deliver therapeutic molecules to their site of action in the patient's body.Dr. Kumar Gaurav...
Even if the development of peptide-targeted liposomes represents a great advance in the use of liposomal drugs for cancer therapy, many critical issues are still unsolved in the development of these innovative drug delivery systems. Advantages and drawbacks of the peptide-mediated active targeting are...
Stefin A-functionalized liposomes as a system for cathepsins S and L-targeted drug delivery Proteolytic activity in the tumor microenvironment is one of the key elements supporting tumor development and metastasis. One of the key families of prote... A Bratov,L Kramer,G Mikhaylov,... - 《...
Liposomes as targeted drug delivery systems in the treatment of breast cancer Solid tumors such as breast cancer have historically provided many challenges to anti-cancer therapy. Therapeutic hurdles to drug penetration in solid tumors include heterogeneous vascular supply and high interstitial pressures wi...
Immunoliposomes represent a rational strategy to achieve targeted drug delivery for cancer treatment. This chapter summarizes the recent developments in th... JW Park,K Hong,DB Kirpotin,... - 《Advances in Pharmacology》 被引量: 212发表: 1997年 Liposomes as targeted drug delivery systems in the...
EGFR-targeted immunoliposomes as a selective delivery system of simvastatin, with potential use in treatment of triple-negative breast cancersEGFR-dependent tumoursimmunoliposomessimvastatintriple negative breast cancersA promising strategy for treatment of EGFR-dependent tumours is EGFR signal transduction ...
SL Huang - 《Advanced Drug Delivery Reviews》 被引量: 369发表: 2008年 Functional liposomes in the cancer-targeted drug delivery Cancer is considered as one of the most severe health problems and is currently the third most common cause of death in the world after heart and infectiou... D ...
The drug delivery systems should positively impact the rate of absorption, distribution, metabolism, and excretion of the drug or other related chemical substances in the body. In addition, the drug delivery system should allow the drug to bind to its target receptor and influence that receptor's...
Recent Advancements of Stimuli-Responsive Targeted Liposomal Formulations for Cancer Drug Delivery Liposomes have gained attention as a well-accepted nanocarrier for several chemotherapeutic drugs and are considered a drug delivery system of choice for a... H Alrbyawi,I Poudel,M Annaji,... - 《Pha...
Liposomes: From a Clinically Established Drug Delivery System to a Nanoparticle Platform for Theranostic Nanomedicine For decades, clinicians have used liposomes, self-assembled lipid vesicles, as nanoscale systems to deliver encapsulated anthracycline molecules for cancer... Wafa’ T. Al-Jamal and ...