(2017). Liposome-based drug co-delivery systems in cancer cells. Mater. Sci. Eng. C Mater. Biol. Appl. 71, 1327-1341. doi: 10.1016/j.msec.2016.11.073Zununi Vahed S, Salehi R, Davaran S, Sharifi S. Liposome‑based drug co‑delivery systems in cancer cells. Mater Sci ...
Lipid based delivery systems are the most studied and promising siRNA delivery systems for systemic application [7], [8], [9]. To ensure a maximal deposition of the siRNA in the target tissue they need to fulfill several requirements. A first, obvious, but sometimes easily forgotten requirement...
Drug delivery systems offer the potential to enhance the therapeutic index of anticancer agents, either by increasing the drug concentration in tumor cells and/or by decreasing the exposure in normal host tissues. This commentary will discuss some of the recent trends in liposome-based drug delivery...
Delivery of drugs into the brain is poor due to the blood brain barrier (BBB). This study describes the development of a novel liposome-based brain-targeting drug delivery system. The liposomes incorporate a diacylglycerol moiety coupled through a linker to a peptide of 5 amino acids selected f...
Lipopolyplex ternary delivery systems incorporating C14 glycerol-based lipids. Mol Pharm 2011; 8: 1831–1847. 31 Condeelis J, Pollard JW. Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell 2006; 124: 263–266. 32 Kobayashi S, Boggon TJ, Dayaram T, Janne ...
Several strategies have been devised to increase the effectiveness of liposome-mediated drug delivery by targeting liposomes to specific tissues and specific cell types. However, while the basic methodology for using liposome-mediated vectors is well developed and has been shown to be safe, the ...
Lipopolyplex ternary delivery systems incorporating C14 glycerol-based lipids. Mol Pharm 2011; 8: 1831–1847. Article CAS PubMed Google Scholar Condeelis J, Pollard JW . Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell 2006; 124: 263–266. Article CAS Pub...
Mathiowitz et al., “Biologically erodable microssheres as potential oral drug delivery systems,” Nature, 1997, 386(6623):410-4. Mattila et al, “Extensive allelic sequence variation in the J region of the human immunoglobulin heavy chain gene locus,” Eur. J. Immunol., 1995, 25:2578...
017) 1327–1341]]]>doi:10.1016/j.msec.2017.10.001Zununi Vahed, SepidehSalehi, RoyaDavaran, SoodabehSharifi, SiminMaterials Science and Engineering C
In conclusion, the combination of CRISPR technology and liposome-based drug delivery systems has proven to be a powerful approach for the efficient delivery of CRISPR components into target cells and/or tissues, thus enabling the specificity and accuracy of genome editing required for safer gene ther...