Clodronate Liposome,氯膦酸盐脂质体 Clodronate Liposome(氯膦酸盐脂质体)是一种在实验动物体内或体外用于清除单核巨噬细胞的即用型液体试剂。以下是对其的详细解析: 一、组成与结构 主要成分:氯膦酸盐(Clodronate),化学名为二氯亚甲基二膦酸二钠。 结构:氯膦酸盐脂质体由同心磷脂双层组成的人造球,包裹了含有氯膦酸...
Clodronate Liposome (Anionic) 氯膦酸盐脂质体(阴离子) Clodronate Liposome (Anionic) 氯膦酸盐脂质体(阴离子) 氯膦酸盐脂质体(阴离子)是一种特殊的脂质体制剂,它结合了氯膦酸盐和脂质体的优点,被广泛用于生物医学研究和治疗领域。以下是对氯膦酸盐脂质体(阴离子)的详细解析: 一、组成与结构 核心成分:氯膦酸盐...
Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro. J Bone Miner Res 1997; 12: 1358-1367Frith JC, Monkkonen J, Blackburn GM, Russell RG, Rogers MJ. Clodronate and ...
Liposomal clodronate eliminates synovial macrophages, reduces inflammation and ameliorates joint destruction in antigen-induced arthritis OBJECTIVES: To investigate the efficacy of a single i.v. dose of clodronate encapsulated within small unilamellar vesicles in suppressing joint inflammatio... Richards,J P...
ClodronateA study was undertaken to determine if the intravenous injection of liposome-encapsulated dichloromethylene diphosphonate (C12MDP; Clodronat), a treatment known to deplete monocytes, as well as liver and spleen macrophages, would reduce the number of macrophages in the retina of animals ...
Liposome-encapsulated clodronate (LEC)MicrogliaSpinal cordNeuropathic painLiposome-encapsulated clodronate (LEC) is a specific depletor of macrophages. Our study characterized the LEC depletory effects, given intrathecally, on spinal microglia and assessed its effects on initiation and maintenance of ...
Monkkonen J, Liukkonen J, Taskinen M, Heath TD, Urtti A. Studies on liposome formulations for intra-articular delivery of clodronate. J Control Release 1995;35(2-3):145-54.Monkkonen J, Liukkonen J, Taskinen M, Heath TD, Urtti A, Studies on liposome formulations for intra-articular ...
名称:DiD Labeled Control Clodronate Liposome (Anionic) DiD标记的对照氯膦酸盐脂质体(阴离子) 纯度:95%+ 储藏条件:常温干燥避光保存 用途:科研 状态:固体/粉末/溶液 保存:冷藏 厂家:西安齐岳生物 特性与功能 荧光特性:DiD标记的脂质体在特定波长光的激发下能够发出荧光,这一特性使其在生物医学研究中具有追踪和观...
Clodronate-loaded liposomes were used as a tool to deplete macrophages in C57BL/6J mice and assess oral osseous bone fill after extraction. In addition to macrophage ablation, osteoclast ablation occurred. Interestingly, depletion of macrophages and osteoclasts via clodronate treatment had differential ...
名称:Control High Potency Clodronate Liposome (Neutral) 纯度:95%+ 储藏条件:常温干燥避光保存 用途:科研 状态:固体/粉末/溶液 保存:冷藏 厂家:西安齐岳生物 相关产品: 人肺靶向甲强龙纳米脂质体,MPS-NSSLs-SPANb 人嗜中性粒细胞肽1(human,neutrophil,peptide,HNP-1)脂质体 ...