Clodronate liposomes are useful tools for in vivo macrophage depletion. In this study, we depleted macrophages using clodronate liposomes to determine their role in the hematopoietic microenvironment in SAMP1/TA-1 and SAMR1 mice. Under clodronate liposome treatment, the response betwee...
3. Van Rooijen N, Sanders A (1994) Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods 174:83–93 4. Van Rooijen N, Bakker J, Sanders N (1997) Transient suppression of macrophage functions by liposome-encapsulated drugs....
For macrophage depletion, liposome-PBS or liposome-Clodronate (Liposoma,CP-005-005) was stereotaxically microinjected into the anterior pituitary (2.5 mm posterior from Bregma, 0.4 mm lateral, 6 mm below pia). The liposomes were delivered to the target site at a rate of 60 nL/min for 500 ...
Macrophage Depletion Kit (Mannosylated) Each mannosylated macrophage depletion kit contains one vial of Clodronate encapsulated mannosylated liposomes (m-Clodrosome) and one vial of plain mannosylated liposome for control (m-Encapsome) Read More ...
3.Van Rooijen N, Sanders A (1994) Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods 174:83–93 4.Van Rooijen N, Bakker J, Sanders N (1997) Transient suppression of macrophage functions by liposome-encapsulated drugs. Tre...
3.Van Rooijen N, Sanders A (1994) Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods 174:83–93 4.Van Rooijen N, Bakker J, Sanders N (1997) Transient suppression of macrophage functions by liposome-encapsulated drugs. Tre...
去除巨噬细胞(depletion of macrophages)。去除巨噬细胞是研究巨噬细胞功能的重要方法,该产品利用巨噬细胞的内吞机制,将膜不通透性的氯磷酸(clodronate)带入细胞内,氯磷酸被释放,当达到一定的浓度时可引发巨噬细胞的凋亡,从而达到去除巨噬细胞的目的。
CCR2 and clodronate liposome monocyte/MΦ depletion experiments. Following infection, mice were administered either 20 μg MC-21 rat anti–mouse CCR2 depleting antibody (Matthias Mack, Regensburg University; ref.28) i.p., daily, or 2.5 mg/mL clodronate liposome suspensions (Liposoma) s.c. at...
4.Claassen, I., Van Rooijen, N., & Claassen, E. (1990). A new method for removal of mononuclear phagocytes from heterogeneous cell populations in vitro, using the liposome-mediated macrophage ‘suicide’ technique. Journal of immunological methods, 134(2), 153-161. ...
3.Van Rooijen N, Sanders A (1994) Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods 174:83–93 4.Van Rooijen N, Bakker J, Sanders N (1997) Transient suppression of macrophage functions by liposome-encapsulated drugs. Tre...