2010. Determination and detection of reactive oxygen species (ROS), lipid peroxidation, and electrolyte leakage in plants. Methods in Molecular Biology, 639, 291-297.Jambunathan N. Determination and detection of reactive oxygen species (ROS), lipid peroxidation, and electrolyte leakage in plants. ...
SLC47A1 belongs to the multidrug and toxin extrusion protein (MATE) family and functions as an organic cation antiporter on the plasma membrane31. Since iron accumulation is the initial signal of ferroptosis resulting in the subsequent generation of reactive oxygen species (ROS)32, we wondered whet...
Reactive oxygen species- (ROS-) induced lipid peroxidation plays a critical role in cell death including apoptosis, autophagy, and ferroptosis. This fundamental and conserved mechanism is based on an excess of ROS which attacks biomembranes, propagates lipid peroxidation chain reactions, and subsequently...
Reactive oxygen species (ROS) and mitochondrial defects in neurons are implicated in neurodegenerative disease. Here, we find that a key consequence of ROS and neuronal mitochondrial dysfunction is the accumulation of lipid droplets (LD) in glia. In Drosophila, ROS triggers c-Jun-N-terminal Kinase...
Reactive oxygen species in plants: their generation, signal transduction, and scavenging mechanisms. Reactive oxygen species (ROS) are a by-product of normal cell metabolism in plants; however, under stress conditions, the balance between production and el... Karuppanapandian,Thirupathi,Moon,... -...
Lack of NEMO expression specifically in hepatocytes leads to complete NF-κB inactivation and, in turn, to sustained JNK activation and reactive oxygen species (ROS) formation promoting cellular death12. Impaired NEMO expression in HCC patients was correlated with poor survival14. In recent publication...
Importantly, our study also identified a crucial role for reactive oxygen species (ROS) in the facilitation of autophagy activation. Antioxidants, such as glutathione and N-acetyl cysteine, significantly abrogated ROS production, and in turn, prevented autophagosome generation and autophagic flux during ...
Omega 3 FAs improve insulin sensitivity by reducing ER stress in mitochondria and enhancing the β-oxidation of FAs, thus decreasing the accumulation of lipids and reactive oxygen species (ROS) [59]. Additionally, omega-3 FAs have a beneficial impact on mitofusin 2, a protein implicated in mito...
ROS, reactive oxygen species. c–e, Number of intestinal peroxisomes, assessed by fluorescence, following MUFA accumulation in worms expressing a peroxisome-localized GFP (GFP–SKL) driven by the intestinal ges-1 promoter (ges-1p::GFP–SKL). c, Zoomed-in images of the intestine. Scale bar, ...
The present study aimed to investigate if heat shock could induce reactive oxygen species (ROS) and iron-dependent ferroptotic cell death in Chlamydomonas reinhardtii in comparison with RSL3-induced ferroptosis. After RSL3 and heat shock (50 °C) treatments with or without inhibitors, Chlamydomonas...