S. McPeek, 2007 Multipoint linkage-disequilibrium mapping with haplotype-block structure. American Journal Of Human Genetics 80: 112-125.M Zheng,MS McPeek.Multipoint linkage-disequilibrium mapping with haplotype-block structure. The American Journal of Human Genetics . 2007...
1) linkage disequilibrium mapping 连锁不平衡定位2) linkage disequilibrium 连锁不平衡 1. Linkage disequilibrium between HLA-DR and -DQ loci in Chinese Han patients with leukemia and their relative donors; 中国汉族白血病患者及其相关人群罕见的HLA-DR/DQ连锁不平衡研究 2. HLA-DR/DQ linkage ...
1998. Linkage disequilibrium mapping in isolated populations: the example of Finland revisited. Proc Natl Acad Sci U S A. 95:12416-23.De la Chapelle A, Wright FA (1998) Linkage disequilibrium mapping in isolated popu- lations: The example of Finland revisited. Proc Natl Acad Sci USA 95: ...
We performed comprehensive SNP validation and linkage disequilibrium (LD) analysis of the c-fos induced growth factor (Figf) gene in Korean population. Out of 32 SNPs, only 9 SNPs were polymorphic in Korean population. Validated SNPs formed a single extended haplotype block with strong LD through...
Multipoint Linkage-Disequilibrium Mapping with Haplotype-Block Structure The HapMap Project is providing a great deal of new information on high-resolution haplotype structure in various human populations. This information has t... M Zheng,MS Mcpeek - 《American Journal of Human Genetics》 被引量:...
Supplementary Table S2 presents the statistics of genome–wide markers used for estimation of LD and effective population size and haplotype block detection. 3.2. Linkage disequilibrium All possible SNP pairs (on the same chromosome) at a distance ≤ 5 Mb, gave 4,479,188 (AR), 4,236,352 (...
De Silva H, Ball R. Linkage disequilibrium mapping concepts. In: Oraguzie NC, Rikkerink EHA, Gardiner SE SH, editors. Association mapping in plants. New York: Springer; 2007. p. 103-32.De Silva HN, Ball RD (2007) Linkage disequilibrium mapping concepts. In: Oraguzie NC, Rikkerink ...
Haplotype blocks:杂合不因为重组而因为连锁,其特征是linkage disequilibrium。 linkage disequilibrium:连锁不平衡:如果在研究过的群体中,A和B两个位点上的等位基因不是独立关联的,我们就说这两个位点是连锁不平衡的,即两个基因连锁。
Along with the magnitude of linkage disequilibrium, knowledge of its decay rates is also a must to determine the resolution obtained during association mapping and judge enough SNP markers on genotyping platforms for marker-assisted breeding [151]. Acquisition of knowledge on LD decay may reveal ...
Linkagedisequilibrium（LD）连锁不。。。GWAS⼊门必看教程：名词解释和基本问题：关联分析：就是AS的中⽂，全称是GWAS。应⽤基因组中数以百万计的单核苷酸多态；SNP为分⼦遗传标记，进⾏全基因组⽔平上的对照分析或相关性分析，通过⽐较发现影响复杂性状的基因变异的⼀种新策略。在全基因组范围内选择...