Optimal design of quantitative-trait loci (QTL) mapping studies requires a precise understanding of the power of QTL linkage versus QTL association analysis, under a range of different conditions. In this article, we investigate the power of QTL linkage and association analyses for simple random sib...
[translate] ainstall program 安装节目 [translate] aA unified test of linkage analysis and rare-variant association for analysis of pedigree sequence data. 连接分析和罕见变形协会一个统一的测试为对家谱序列数据的分析。 [translate] 英语翻译 日语翻译 韩语翻译 德语翻译 法语翻译 俄语翻译 阿拉伯语翻译 ...
number and seed number per pod using the reference skeleton linkage map; (4) validation and fine mapping of the major QTLs by regional association analysis; and (5) dissection of the genetic basis of the colocalised QTLs for pod number and seed number per pod by conditional QTL analysis. Re...
For complex diseases, investigators often map the disease of interest first by linkage analysis, followed by association analysis in regions with evidence for linkage. In this setting, genotypes will be available for most family members for the genetic markers used in linkage analysis and will be ...
Association analysis of APOE polymorphism An association study of APOE polymorphism and LDL-C concentrations was performed using both model 1 and model 2 covariate adjustment strategies in the North and South Dakota population only, as linkage to 19q was specific to the South Dakota center. A tota...
Statistical analysis To evaluate STR markers associated with the difference between IgE-high and IgE-normal asthmatics, the STR markers with significantly different allele frequencies in two asthma subtypes were sought by v2 test, in which the significant level was estimated by Monte-Carlo simula- ...
Data were taken on agronomic and morphological traits and the combined analysis was performed by a mixed linear model. The adjusted means of plant height,... S Taba,J Diaz,J Franco,... - 《Crop Science》 被引量: 152发表: 1998年 Genome-wide association study (GWAS) reveals the genetic ...
Genetic architecture of kernel-related traits in sweet and waxy maize revealed by genome-wide association analysis Introduction: Maize (Zea mays L.) is one of the most important crops worldwide, the kernel size-related traits are the major components of maize grain yiel... J Qu,D Yu,W Gu...
Articles on the following areas are especially welcome: genetic factors of monogenic and complex disorders, genome-wide association studies, genetic epidemiology, cancer genetics, personal genomics, genotype-phenotype relationships and genome diversity. • Medical genetics • Human genome analysis • ...
The effects of admixture within individuals are considerably more difficult to assess and have been left for future analysis. Haplotype and LD Selection Under certain circumstances, haplotypes may be a useful way to reduce the complexity of candidate-gene association analyses. Discrimination between ...