In the GWAS analysis, no variants reached genome wide significance (5 × 108). However, using a lower significance threshold for regional association under a linkage peak (p < 105), 7 associated variants were identified in two regions under the Chr11 peak. We identified a 6.5 mb area of ...
As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In "Linkage Disequilibrium and Association Mapping: Analysis and Applications", scientists from around the world, who are leaders in this field, contribute their vast experien...
Using combined-linkage analysis and association mapping, PZE-101066560 on chromosome 1, associated with kernel width and with 100-kernel weight in the association panel, was co-localized within the QTL interval of qKW1-3 for kernel width in the RILs. Two annotated genes in the candidate region...
Molecular Diversity and Association Analysis of Drought and Salt Tolerance in Gossypium hirsutum L. Germplasm Association mapping is a useful tool for the detection of genes selected during plant domestication based on their linkage disequilibrium (LD). This study ... YH Jia,JL Sun,XW Wang,... ...
当当中华商务进口图书旗舰店在线销售正版《海外直订Linkage Disequilibrium and Association Mapping: Analysis and Applicati 连锁不平衡与关联映射:分析与应用》。最新《海外直订Linkage Disequilibrium and Association Mapping: Analysis and Applicati 连锁不平衡与关
Joint QTL Linkage Mapping for Multiple-Cross Mating Design Sharing One Common Parent. Background: Nested association mapping (NAM) is a novel genetic mating design that combines the advantages of linkage analysis and association mapping. Thi... H Li,Bradbury,Peter,... - 《Plos One》 被引量:...
• Medical genetics • Human genome analysis • Gene cloning and mapping • Linkage and association analyses • Rare variants in diseases and phenotypes • Mutational analysis • Susceptibility genes to multifactorial disorders • Human evolution • Cancer genetics • Gene therapy • ...
Designs for Linkage Analysis and Association Studies of Complex Diseases For complex diseases which often involve function of multi-genetic variants each with small or moderate effect, linkage analysis has little power compared to association studies. In this chapter, we give a brief review of design...
Optimal design of quantitative-trait loci (QTL) mapping studies requires a precise understanding of the power of QTL linkage versus QTL association analysis, under a range of different conditions. In this article, we investigate the power of QTL linkage and association analyses for simple random sib...
The instrument can sequence plasmid, BAC end, and double-stranded templates and can be used with PE Biosystems' BigDye Primer and Terminator chemistries and Linkage Mapping Set Version 2 fragment analysis chemistries as well as with various other chemistries. PE BIOSYSTEM GETS 500 ABI PRISM 3700 ...