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USF1 is located on chromosome 1q22-23, a region with evidence for linkage to type 2 diabetes and various traits of the metabolic syndrome in Chinese and other populations. The aim of this study was to investigate the linkage and association of USF1 with type 2 diabetes and the metabolic ...
This paper describes our co-design methodology and the resulting software, presenting case studies demonstrating its use in test analyses, and discussing methodological implications in the context of the Genealogies of Knowledge corpus-based approach to the study of medical, scientific, and political con...
Z. (2007). Linkage and association studies in African- and Caucasian-American populations demonstrate that SHC3 is a novel susceptibility locus for nicotine depend- ence. Molecular Psychiatry, 12, 462-473. doi:10.1038/ sj.mp.4001933Li MD, Sun D, Lou XY, Beuten J, Payne TJ, Ma JZ. ...
The transmission/disequilibrium test for a three-site haplotype moving window again provided multiple positive results. The background linkage disequilibrium (LD) of the region was studied in eight populations of European origin. A complicated pattern was revealed, with the pairwise tests producing ...
Analysis of population structure demonstrated evidence of shared genetic ancestry between studied cross-bred population and both Red-Angus and Mongolian breeds. Among all studied cattle populations, the highest and lowest levels of linkage disequilibrium (LD) per Kb were detected in Holstein and Rash...
However, it is important to note that these results have limited generalizability, and the impact of the treat-all policy in the broader context of China remains unclear. To assess the impact of the treat-all policy, we analyzed the time from diagnosis to ART initiation, the CD4 + T-...
However, the role of education might be sensitive to sociocultural context. Similar to our findings, other investigations from the Rotterdam Study,36 the Rochester Epidemiology Project,37 and the Baltimore Longitudinal Study of Aging38 reported a lack of association between dementia incidence and ...
Climate change is projected to intensify drought conditions, which may increase the risk of diarrheal diseases in children. We constructed log-binomial generalized linear mixed models to examine the association between diarrhea risk, ascertained from global-scale nationally representative Demographic and Heal...
linkage of carcasses with cultural finds), are common in the Middle Pleistocene record of western Eurasia42. Such associations allow paleoecological investigations of proboscidean diets and habitats to shed light also on hominin environments and subsistence (e.g.,45,46). Here we show that the ...