To understand the ligand binding mechanism, a comparison between ligand-free and ligand-bound GlnBP was made. The conformational space of ligand-bound GlnBP explored herein shows that ligand binding expands the conformational space with respect to that of ligand-free GlnBP31(Supplementary Fig.4). ...
The ligand binding affinities, and sensitivity to Mg2+, together with results from mutagenesis, suggest that Co and Ci are partially unfolded species compromised in key loop-loop interactions present in the fully folded Cc. These data verify that the ligand-bound riboswitches may dynamically fold ...
In this work, we put forward the provocative hypothesis that the active, ligand-bound RTK dimers from unrelated subfamilies can associate into heterooligomers with novel signaling properties. This hypothesis is based on a quantitative FRET study that monitors the interactions between EGFR and VEGFR2 ...
M. RNA Dynamics by Design: Biasing Ensembles Towards the Ligand-Bound State. Angew. Chem., Int. Ed. Engl. 2010, 49, 5731-5733.Stelzer AC, Kratz JD, Zhang Q, Al-Hashimi HM. 2010. RNA dynamics by design: biasing ensembles towards the ligand-bound state. Angew. Chem. Int. Ed. Engl...
网络释义 1. 配体结合受体 ...20世纪90年代,研究人员才在动物实验中证实,一些配体结合受体(ligand-bound receptors)需要内化进入内涵体,才能进 …www.wiki8.com|基于14个网页必应词典应用 准确权威无广告去官网了解更多 下载手机版必应词典 iOS Windows Phone Android 体验P C 版必应词典Win32 版Microsoft 商店 ...
Ligand-bound TRβ binds the RhoB promoter and upregulates transcriptional activation.Sayaka IchijoFumihiko FuruyaHiroki ShimuraYoshitaka HayashiKazuya TakahashiKazuyasu OhtaTetsuro KobayashiKenichiro Kitamura
Ligand-bound Structures and Site-directed Mutagenesis Identify the Acceptor and Secondary Binding Sites of Streptomyces coelicolor Maltosyltransferase GlgE 来自 万方 喜欢 0 阅读量: 24 作者:Syson,Karl,Stevenson,EM Clare,Miah,Farzana,Barclay,J Elaine,Tang,Minhong ...
Ligand-bound thyroid hormone receptor contributes to reprogramming of pancreatic acinar cells into insulin-producing cells. J Biol Chem. 2013; 288:16155-16166. [PubMed: 23595988]Furuya F, Shimura H, Asami K, Ichijo S, Takahashi K, ... Furuya,Shimura,Asami,... - 《Journal of Biological Che...
ligand is present in three of them. The electron density maps show that there is barely any density for 2 ADP molecules. In the case of the third ADP molecule, there are two broken pieces of density into which the ADP molecule is fitted. This ADP ligand may not be bound or the fit ...
Conformational plasticity of ligand-bound and ternary GPCR complexes studied by 19F NMR of the β1-adrenergic receptor J. Niclas Frei, Richard W. Broadhurst, Mark J. Bostock, Andras Solt, Andrew J. Y. Jones, Florian Gabriel, Aditi Tandale, Binesh Shrestha & Daniel Nietlispach ...