Ligand-bound quantum dot probes for studying the molecular scale dynamics of receptor endocytic trafficking in live cells. ACS Nano. 2008; 2 :1153–1166. [ PubMed ]Rajan SS, Liu HY, Vu TQ (2008) Ligand-bound quantum dot probes for studying the molecular scale dynamics of recep...
网络释义 1. 配体结合受体 ...20世纪90年代,研究人员才在动物实验中证实,一些配体结合受体(ligand-bound receptors)需要内化进入内涵体,才能进 …www.wiki8.com|基于14个网页必应词典应用 准确权威无广告去官网了解更多 下载手机版必应词典 iOS Windows Phone Android 体验P C 版必应词典Win32 版Microsoft 商店 ...
Ligand-bound thyroid hormone receptor contributes to reprogramming of pancreatic acinar cells into insulin-producing cells. J Biol Chem. 2013; 288:16155-16166. [PubMed: 23595988]Ligand-bound thyroid hormone receptor contributes to ... Furuya,Shimura,Asami,... - 《Journal of Biological Chemistry》...
Ligand-bound TRβ binds the RhoB promoter and upregulates transcriptional activation.Sayaka IchijoFumihiko FuruyaHiroki ShimuraYoshitaka HayashiKazuya TakahashiKazuyasu OhtaTetsuro KobayashiKenichiro Kitamura
Protein dynamics plays key roles in ligand binding. However, the microscopic description of conformational dynamics-coupled ligand binding remains a challenge. In this study, we integrate molecular dynamics simulations, Markov state model (MSM) analysis
with a primary focus on ligand-bound states. Our analysis reveals that while AlphaFold3 shows improved performance over AlphaFold2 in predicting overall GPCR backbone architecture, significant discrepancies persist in ligand-binding poses, particularly for ions, peptides, and proteins. Despite advancements...
The nuclear receptor retinoid acid receptor-related orphan receptor γt (RORγt) is a master regulator of the Th17/IL-17 pathway that plays crucial roles i... X Li,M Anderson,D Collin,... - 《Journal of Biological Chemistry》 被引量: 7发表: 2017年 apo and ligand-bound rorγt structu...
Stimulation of SIRT1-regulated FoxO protein function by the ligand-bound vitamin D receptor. Mol Cell Biol. 2010;30:4890–900. CrossRef Masten AR. ... JH White - 《Reviews in Endocrine & Metabolic Disorders》 被引量: 173发表: 2012年 Role of \\{SIRT1\\} and \\{FOXO\\} factors in...
Receptor recognition factors exist that recognizes the specific cell receptor to which a specific ligand has been bound, and that may thereby signal and/or initiate the binding of the transcription factor to the DNA site. The receptor recognition factor
1995 . Evidence for distinct ligand-bound conformational states of the multifunctional Escherichia coli repressor of biotin biosynthesis . Biochemistry 34 : 16624 – 16631 .Xu, Y., Nenortas, E., and Beckett, D. (1995) Evidence for distinct ligand- bound conformational states of the ...