Loading ligand-receptor database ###We provide a database with pairwise ligand and receptor genes for users. Load the database and filter the LR pairs, requiring both ligand and receptor genes to be expressed in a certain percentage of cells (or spots). LR_df = hn.pp.load_lr_df() ex...
Loading ligand-receptor database ###We provide a database with pairwise ligand and receptor genes for users. Load the database and filter the LR pairs, requiring both ligand and receptor genes to be expressed in a certain percentage of cells (or spots). LR_df = hn.pp.load_lr_df() ex...
Novel compounds include the group R7-SO2-S-C(R3)2-C(R4)2-(CH2)n- Either one such group is bonded to R6 or one or more such groups are bonded to a ligand or receptor, whereupon R7 may be replaced by a radical derived by removal of the sulfhydryl group from luciferase. Either R3 ...
and the highest level of receptor; we refer to these as the major-transmitter and major- receiver, respectively, and to the pair as the major-signalling pair (Supplementary Data 6; these major-signalling pairs are likely to Figure 4 | Ligand–receptor signalling network interface (hive view)....
Ligand/receptor pair-binding compounds 来自 百度文库 喜欢 0 阅读量: 10 申请(专利)号: EP19870103808 申请日期: 1984-02-17 公开/公告号: EP0234600A1 公开/公告日期: 1987-09-02 申请(专利权)人: THE UPJOHN COMPANY;THE TEXAS A&M UNIVERSITY SYSTEM 发明人: Baldwin Thomas Oakley c/o ...
a manually curated comprehensive database of LR interaction pairs in humans and mice comprising 3398 human LR pairs and 2033 mouse LR pairs, through text mining and manual verification of known protein-protein interactions using the STRING database, with literature-supported evidence for each pair. ...
We show here that Norrin and Fz4 function as a ligand-receptor pair based on (1) the similarity in vascular phenotypes caused by Norrin and Fz4 mutations in humans and mice, (2) the specificity and high affinity of Norrin-Fz4 binding, (3) the high efficiency with which Norrin induces Fz4...
and J. Banchereau, CD40-CD40 ligand: a multifunctional receptor- ligand pair. Adv Immunol, 1996. 61: p. 1-77... None - 《Science》 被引量: 0发表: 2008年 TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells. To examine the role...
1) expensive labelling of the macromolecule is not required, as only the ligand signals are detected; 2) no limitations about the upper size of the protein, using a high-molecular-weight receptor results, indeed, in readily detectable ligand signals; 3) small amount of receptor necessary (typic...
ligand–receptor pair is expressed. Medians are shown as green lines. For all plots ina–ca threshold of 10 TPM was used. (d) Distribution of the number of possible ligand–receptor paths between ligand-secreting cell A and receptor-expressing cell B calculated for all 144 × 144 possible ...