16.4.1 Ligand-Gated Channels The ligand-gated channels, also known as agonist-gated, are a group of ion channels that open or close in response to binding of a chemical messenger (ligand), as opposed to voltage-gated ion channels (see earlier). Although structurally and functionally diverse,...
Ligand-gated ion channels mediate the rapid transfer of information across nerve synapses in the brain and peripheral nervous system. They are also located in extrasynaptic regions of neurons as well as on glia and non-neuronal tissue. These receptors are composed of four to five protein subunits...
a slow voltage-gated channel very permeable to calcium ions and slightly permeable to sodium ions, existing in three subtypes designated L, M, and N and located throughout the body; calcium channels are the main cause of action potentials in certain smooth muscles, and the N channels regulate...
Many important ion channels are ligand-gated, and they show a great degree of homology at the genetic level. The Ligand-gated ion channels are classified into three superfamilies: The Cys-loop receptorsanionic GABAA α1 (GABRA1), α2 (GABRA2), α3 (GABRA3), α4 (GABRA4), α5 (...
Free Essay: Ligand-gated ion channels, such as GABAA receptors, generate a current by moving ions through the pore of the channel across the membrane. Ion...
Define ligand. ligand synonyms, ligand pronunciation, ligand translation, English dictionary definition of ligand. n. An ion, molecule, or molecular group that binds to another chemical entity to form a larger complex. American Heritage® Dictionary of
Pentameric ligand-gated ion channels (pLGICs) mediate synaptic transmission and are sensitive to their lipid environment. The mechanism of phospholipid modulation of any pLGIC is not well understood. We demonstrate that the model pLGIC, ELIC (Erwinia lig
Google Share on Facebook ligand (redirected fromLigands) Thesaurus Medical Encyclopedia li·gand (lī′gənd, lĭg′ənd) n. An ion, molecule, or molecular group that binds to another chemical entity to form a larger complex. [From Latinligandus, gerundive ofligāre,to bind; seeligate....
P2x receptors bring new structure to ligand-gated ion channels P2x receptors are cation-selective ion channels that open on binding to extracellular ATP; they play a role in fast synaptic transmission between neurones,... Annmarie,Surprenant,and,... - 《Trends in Neurosciences》 被引量: 570...
A nomenclature for ligand-gated ion channels The ligand-gated ion channels that participate in fast synaptic transmission comprise the nicotinic acetylcholine, 5-hydroxytryptamine3 (5-HT3), 纬-aminobu... Graham,L.,Collingridge,... - 《Neuropharmacology》 被引量: 757发表: 2009年 Regulation of lig...