miR-4262 was the target gene of LIFR-AS1. We also found that miR-4262 abrogated the functions of LIFR-AS1 on cell proliferation, apoptosis, migration and invasion of glioma cells in the NF-κB pathway. Conclusion LIFR-AS1 could suppress the proliferation, migration and invasion and promote ...
Colorectal cancer (CRC), photodynamic therapy (PDT) Microarrays analysis Long non-coding RNA (lncRNA) LIFR-AS1 miR-29a TNFAIP3 1. Introduction Colorectal Cancer (CRC) has been regarded as a common digestive system malignancy [1]. Since Photodynamic therapy (PDT) has been classified as a basic...
Functionally, loss-of-function studies indicated that LIFR-AS1 knockdown decreased the proliferation, migration, and invasion of PC cells in vitro. Mechanistically, we found that METTL3 induced m 6 A hyper-methylation on the 3′ UTR of LIFR-AS1 to enhance its mRNA stability and LIFR-AS1 could...
Conclusions Taken together, macrophages-derived exosomal lncRNA LIFR-AS1 can promote osteosarcoma cell proliferation, invasion, and restrain cell apoptosis via miR-29a/NFIA axis, which can act as a potential novel therapeutic target for osteosarcoma therapy....
Long noncoding RNA (lncRNA) LIFR‐AS1 is a tumor suppressor gene in colorectal cancer, but its effect and underlying mechanism in SOC are still unclear. Therefore, this study focuses on unveiling the regulatory mechanism of LIFR‐AS1 in SOC....
Long non-coding RNA LIFR-AS1 is low-expressed in many cancers, but its functions in papillary thyroid carcinoma (PTC) were not defined and require further study. The relationship between LIFR-AS1 expression and clinicopathological characteristics of patients with PTC was statistically analyzed. The ...
The long non-coding RNA (lncRNA) LIFR-AS1 has been shown to be involved in the development of several human cancers. This study was designed to determine the expression profile and role of lncRNA-LIFR-AS1 in human thyroid cancer. The results showed significant (p < 0.05) upregulation of ...
LIFR-AS1proliferationapoptosismetastasismiR-4262NF-kappa B pathwayAim: This study aimed to explore the role of lncRNA leukemia inhibitory factor receptor antisense RNA 1 (LIFR-AS1) on glioma and its underlying molecular mechanism.Ding, HaiTao
LncRNA LIFR-AS1过表达对非小细胞肺癌细胞生物学性能的影响doi:10.3969/j.issn.1002-266X.2019.34.013林忠琨李锴男王雷Shandong Medical Journal