Central infusions of leptin and GLP-1-(7-36) amide differentially stimulate c-FLI in the rat brain. Am J Physiol 271(4 Pt 2): R1096- 1100,1996. PMID: 8898006.Van Dijk G, Thiele TE, Donahey JC, Campfield LA, Smith FJ, Burn P, Bernstein IL, Woods SC, Seeley RJ 1996 Central ...
结果 2组患者治疗前的Glp-1、Leptin及Ghrelin水平比较,差异无统计学意义(P>0.05);研究组治疗后的Glp-1、Leptin显著高于治疗前及对照组治疗后,差异有统计学意义(P<0.05);研究组治疗后的Ghrelin水平显著低于治疗前及对照组治疗后,差异有统计学意义(P<0.05)。结论 二甲双胍联合地特胰岛素可提升T2DM患者的Leptin和...
下丘脑-垂体轴(如 HPA 轴、HPT 轴以及下丘脑-垂体-性 腺轴等)、脂肪-胰 岛轴、细胞因子(如 IL-1,IL-6,TNF)、丙酮酸、游离脂肪酸(FFA)、能量平衡、性别、年龄、种属差异以及某些激素如神经肽 Y(neuroI peptide Y,NPY)、增食欲素、MCH、POMC、GLP-1、CART 等有关。
The physiological control of feeding behavior involves modulation of the intake inhibitory effects of gastrointestinal satiation signaling via endogenous hindbrain leptin receptor (LepR) and glucagon-like-peptide-1 receptor (GLP-1R) activation. Using a v
The LepR-expressing neurons in the AP modulate metabolic and energy status [55]. Leptin regulates gastrointestinal satiation signals, such as gastric distension, CCK or glucagon-like-peptide-1 (GLP-1) by acting on LepR in mNTS/AP neurons [56], [57], [58], [59]. Knockdown of LepR in ...
目的探讨地特胰岛素对不同BMI的2型糖尿病患者胰高血糖素样肽-1(GLP-1)、瘦素(Leptin)和胃肠运动功能及促生长素(Ghrelin)水平影响。方法随机选取佛山市中医院2型糖尿病患者60例,根据体质量指数(BMI)分为正常BMI组和超重组,两组患者均起始加予地特胰岛素联合诺和龙治疗,1次/d,检测治疗前和治疗2年后GLP-1、Lepti...
Central infusions of leptin and GLP-1-(7–36) amide differentially stimulate c-FLI in the rat brain Am. J. Physiol., 271 (1996), pp. R1096-R1100 Google Scholar 75 J.G Veening, L.W Swanson, W.M Cowan, R Nieuwenhuys, L.M.G Geeraedts The medial forebrain bundle of the rat. ...
Central infusions of leptin and GLP-1-(7–36) amide differentially stimulate c-FLI in the rat brain Am. J. Physiol, 271 (1996), pp. R1096-R1100 View in ScopusGoogle Scholar 45 A Yoshimura, T Ohkubo, T Kiguchi, N.A Jenkins, D.J Gilbert, N.G Copeland, T Hara, A Miyajima A nov...
Metabolic Marker Assays: Adiponectin, GLP-1, Insulin, Leptin and ResistinMouse Adiponectin GLP-1 Human InsulinMouse/Rat Insulin Human Leptin Mouse Leptin Rat LeptinMouse/Rat ResistinSelen A. StromgrenMichael TsionskyTatiana PlissovaAnu Mathew
水平比较,差异无统计学意义 (P>0.05);研究组治疗后的 Glp-1、Leptin 显著高于治疗前及对照组治疗后,差异有 统计学意义(P<0.05);研究组治疗后的 Ghrelin 水平显著低于治疗前及对照组治疗 后,差异有统计学意义(P<0.05).结论 二甲双胍联合地特胰岛素可提升 T2DM 患者 的 Leptin 和 GLP-1 水平,降低 Ghrelin ...