(2011) LC-MS-Based metabolomics. Methods Mol. Biol. 708, 213- 228Bajad S, Shulaev V. LC-MS-based metabolomics. Methods Mol Biol 2011; 708: 213-228.Bajad S, Shulaev V. 2011. LC-MS-based metabolomics. In Metz TO (ed.), Metabolic Profiling Methods In Molecular Biology, vol. 708....
An altered metabolism often points to a disease, so it is pivotal to understand the mechanisms controlling endogenous metabolites. This need has given rise to metabolomics, the comprehensive study of the small molecule metabolites that reflect the complex network of b...
The annotation and identification of metabolites is a current bottleneck in non-targeted metabolomics studies. Although accurate measurement of m/z is applied routinely in UPLC–MS applications to putatively annotate metabolites, the acquisition of MS/MS or MS n data is required to deduce structural ...
MetabolomicsSPCALC–MSPlasmaTime since last mealObservational studyIn metabolomics studies, liquid chromatography mass spectrometry (LC-MS) provides comprehensive information on biological samples. However, extraction of few relevant metabolites from this large and complex data is cumbersome. To resolve this...
LC-MS-Based Metabolomics in the Identification of Biomarkers Pertaining to Drug Toxicity: A New Narrative At present, LC-MS platform is a workhorse in metabolomics and other research fields, e.g., drug metabolism and pharmacokinetics. In some cases, drug ... X Qin,JM Hakenjos,F Li 被引量...
et al. Gut microbiota and fecal metabolites in captive and wild North China leopard (Panthera pardus japonensis) by comparsion using 16 s rRNA gene sequencing and LC/MS-based metabolomics. BMC Vet Res 16, 363 (2020). https://doi.org/10.1186/s12917-020-02583-1 Download citation Received15...
The area under curve was 0.786 and 0.773 for discovery stage and validation stage samples, respectively. These data show that the established pseudotargeted method is a complementary one of targeted and nontargeted methods for metabolomics study. 展开 年份: 2014 ...
LC-MS-based Metabolomics in Traditional Chinese Medicines Research: Personal Experiences 来自 国家科技图书文献中心 喜欢 0 阅读量: 130 作者:M Qian,JD Xu,M Kong,S Hong,H Zhu,SS Zhou,SL Li 摘要: 摘要: 关键...
Metabolomics 2015; 11: 1721- 32.Kim, D.-H., Achcar, F., Breitling, R., Burgess, K. E., and Barrett, M. P. (2015) LC-MS-based absolute metabolite quantification: application to metabolic flux measurement in trypanosomes. Metabolomics 11, 1721-1732...
Metabolomics has been applied to explore altered metabolite profiles in disease and identify unique metabolic signatures in recent years. We aim to charact