Zhang R,Hu P,Zang Q,et al.LC-MS-based metabolomics reveals metabolic signatures related to glioma stem-like cell self-renewal and differentiation[J].RSC Adv,2017,7(39):24221-24232.R. Zhang, P.S. Hu, Q.C. Zang, X.F. Yue, Z. Zhou, X.Y. Xu, J. Xu, S.S. Li, Y.H. ...
LC-MS metabolic profiling of Arabidopsis thaliana plant leaves and cell cultures: Optimization of pre-LC-MS procedure parameters Hereby, the magnitude of the matrix effect observed in the ensuing LC-MS based met...
et al. Interrogation of the mammalian gut–brain axis using LC–MS/MS-based targeted metabolomics with in vitro bacterial and organoid cultures and in vivo gnotobiotic mouse models. Nat Protoc 18, 490–529 (2023). https://doi.org/10.1038/s41596-022-00767-7 Download citation Received23 ...
Metabolomics is a rapidly growing area of scientific research. Global metabolic profiling employing technological platforms such as nuclear magnetic resonance (NMR) or mass spectrometry (MS) is an increasingly powerful tool for studying biological phenomena1. Thus far, metabolomics research has mostly focu...
Validated LC–MS/MS method for the determination of 3-hydroxflavone and its glucuronide in blood and bioequivalent buffers: Application to pharmacokinetic,... The purpose of this study is to develop an UPLC–MS/MS method to quantify 3-hydroxyflavone (3-HF) and its metabolite, 3-hydroxyflavone...
MS-DIAL was launched as a universal program for untargeted metabolomics that supports multiple instruments (GC/MS, GC/MS/MS, LC/MS, and LC/MS/MS) and MS vendors (Agilent, Bruker, LECO, Sciex, Shimadzu, Thermo, and Waters). Part of the spectrum algorithm in MZKit is developed based on...
这些信息可从烟瘾治疗所在检查治疗程序是否符合和外科部门在决定肺移植资格的时候得到。 现在已有好多的测量血浆中尼古丁和它的两种代谢物的分析方法,包括GC/MS和LC/MS。然而,来自法国Aix-Marseille大学的研究人员Audrey Boulamery,Natalia Liachenko和 Nicolas Simon却在他们试图纠正那些修改...阅读全文 基础...
To optimize for high proteome coverage, protein and peptide-level ion exchange fractionation were assessed using rat liver microsomes and S9 fractions. 2D-(SCX-RP)-LC–MS/MS analysis with peptide fractionation was subsequently employed for rat, mouse and human samples, yielding between 1400 and ...
Although LC-MS untargeted metabolomics continues to expand into exiting research domains, methodological issues have not been solved yet by the definition of unbiased, standardized and globally accepted analytical protocols. In the present study, the response of the plasma metabolome coverage to specific...
(at harvest time)Ripe (ready-to-eat stage) Pulp of 3–4 pieces of fruit to compose a sample for each RS and variety GC-FID/APCI-TOF MS Analysis of 27 metabolites belonging to different chemical families Evaluation of the potential of GC-APCI-MS in Food Metabolomics and comparison with ...