原名:Recent advances in LC-MS-based metabolomics for clinical biomarker discovery 译名:用于临床生物标志物发现的LC-MS代谢组学的最新进展 期刊:Mass Spectrometry Reviews IF:10.946 发表时间:2022.05 通讯作者:陳朝榮 通讯作者单位:中国医药大学中西医...
我司可提供LC-MS非靶向代谢组学和定制靶向开发服务，为从事疾病的生物标志物研究的科研工作者提供相关服务。参考文献 [1]Jian G, Tao H.Comparison of Full-Scan, Data-Dependent, and Data-Independent Acquisition Modes in Liquid Chromatography–Mass Spectrometry Based Untargeted Metabolomics[J]. Analytical Chem...
Chemical derivatization of metabolites offers an opportunity to improve the overall analytical performance of liquid chromatography mass spectrometry (LC-MS) based metabolomics. This review highlights recent progresses (since 2016) in the field of chemical derivatization LC-MS for both targeted and ...
本篇由哈尔滨医科大学药物研究重点实验室在Journal of Pharmaceutical and Biomedical Analysis杂志发表题为“LC–MS based urinary metabolomics study of the intervention effect of aloe-emodin on hyperlipidemia rats”的研究论文,该研究采用LC-MS代谢组学研究芦荟大黄素能对高脂血症的降脂作用。 标题:基于LC-MS代谢...
关键词:MALDI-MSI质谱成像,Tartary buckwheat苦荞,Spatial–temporal metabolomics时空代谢组学 01 前言 苦荞富含膳食纤维、蛋白质和次生代谢产物,具有抗氧化、抗炎、抗癌、降血糖、降血压和降血脂等多种功效。一般来说,谷物的发育过程可以划分为不同的阶段,这些阶段表现出可识别的代谢变化。先前的研究表明,成熟的黑色和...
Overall, the combination of genetically-modified animal models and metabolomics provide a powerful tool to characterize APAP-induced liver toxicity and undercover novel mechanism.doi:10.1096/fasebj.23.1_supplement.760.4Chi ChenFood Science and NutritionUniversity of MinnesotaSt PaulMNKristopher W Krausz...
关键词:MALDI-MSI 质谱成像,Tartary buckwheat 苦荞,Spatial–temporal metabolomics 时空代谢组学, flavonols 黄酮醇 01 前言 苦荞富含膳食纤维、蛋白质和次生代谢产物,具有抗氧化、抗炎、抗癌、降血糖、降血压和降血脂等多种功效。一般来说,谷物的发育过程可以划分为不同的阶段,这些阶段表现出可识别的代谢变化。先前的...
LC-MS-Based Metabolomics in the Identification of Biomarkers Pertaining to Drug Toxicity: A New Narrative At present, LC-MS platform is a workhorse in metabolomics and other research fields, e.g., drug metabolism and pharmacokinetics. In some cases, drug ... X Qin,JM Hakenjos,F Li 被引量...
Liquid chromatography-mass spectrometry (LC-MS)Metabolite annotationMetabolomicsThe annotation and identification of metabolites is a current bottleneck in non-targeted metabolomics studies. Although accurate measurement of m/z is applied routinely in UPLC–MS applications to putatively annotate metabolites, ...
The wide applications of liquid chromatography - mass spectrometry (LC-MS) in untargeted metabolomics demand an easy-to-use, comprehensive computational workflow to support efficient and reproducible data analysis. However, current tools were primarily d