Latest Research and Reviews Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during aging Using single-cell imaging of a fluorescent chaperone-mediated autophagy (CMA) reporter and RNA sequencing data, the authors present a resource on basal CMA activity acros...
All Research & Reviews News and Comment An E3 ligase and autophagy adaptor regulates tau proteostasis through nested phase separation Mutations in the gene encoding the E3 ubiquitin ligase TRIAD3A cause adult-onset neurodegenerative disorders. We reveal that the ubiquitin ligase activity of TRIAD3A prom...
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Therefore, this article reviews the methods and mechanisms for breaking through the BBB, as well as the current research progress on this mechanism. Keywords: cerebrovascular disease; blood–brain barrier; passive diffusion; receptor-mediated transport; adsorption-mediated transport; carrier-mediated ...
Currently, many studies utilize various methods to monitor autophagy flux. (1) In dynamic detection, like the dual fluorescence mRFP-GFP-LC3 system, static technology merely detects the outcome of autophagy. However, dynamic technology focuses on whether the process of autophagy is unobstructed or ...
Find all the latest on fungal cells at Medical Xpress. Your go-to source for news, research, and medical breakthroughs.
research on tumor metastasis, encompassing drug resistance, restricted animal models, inadequate biomarkers and early detection methods, as well as heterogeneity among others. It is anticipated that this comprehensive review will significantly contribute to the advancement of cancer metastasis research. ...
Three main morphologies have been described: apoptosis, cell death with autophagy and necrosis. Their inherent dy... LM Engelbrecht - 《Experimental Cell Research》 被引量: 117发表: 2011年 The influence of capsulation and lipooligosaccharide structure on neutrophil adhesion molecule expression and ...
Three main morphologies have been described: apoptosis, cell death with autophagy and necrosis. Their inherent dy... B Loos,S Genade,B Ellis,... - 《Experimental Cell Research》 被引量: 144发表: 2011年 The influence of capsulation and lipooligosaccharide structure on neutrophil adhesion molecule...
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