Janku F, McConkey DJ, Hong DS, Kurzrock R. Autophagy as a target for anticancer therapy. Nat Rev Clinical Oncol 2011 ; 8:528-39; PMID: 21587219 ; http://dx.doi.org/ 10.1038/nrclinonc.2011.71Janku F , McConkey DJ , Hong DS , Kurzrock R ( 2011 ). Autophagy as a target for...
Autophagy as a Target for Anticancer Therapy and Its Modulation by Phytochemicals Journal of Food & Drug AnalysisMi-Kyung KimDong Hoon SuhJungyeob SeoungHee Seung KimHyun Hoon ChungYong-Sang Song
Under normal conditions, autophagy remains at a low basal level, which is essential for the maintenance of cellular homeostasis via the turnover of energy and cellular building material1,6. However, dysregulated autophagy could be implicated in diverse pathological processes, such as metabolic diseases...
Autophagy as a target for anticancer therapy. Nat Rev Clin Oncol 2011; 8: 528–539. Article CAS PubMed Google Scholar Glick D, Barth S, Macleod KF . Autophagy: cellular and molecular mechanisms. J Pathol 2010; 221: 3–12. Article CAS PubMed PubMed Central Google Scholar Cecconi F, ...
Janku F, Mcconkey DJ, Hong DS, Kurzrock R (2011) Autophagy as a target for anticancer therapy. Nat Rev Clin Oncol 8:528–539 CAS PubMed Google Scholar Apel A, Herr I, Schwarz H, Rodemann HP, Mayer A (2008) Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy....
Janku F, McConkey DJ, Hong DS, Kurzrock R (2011) Autophagy as a target for anticancer therapy. Nat Rev Clin Oncol 8:528–539 ArticleCASPubMedGoogle Scholar Jaramillo MC, Zhang DD (2013) The emerging role of the Nrf2–Keap1 signaling pathway in cancer. Genes Dev 27:2179–2191 ...
[6]Pliszka M, Szablewski L. Glucose transporters as a target for anticancer therapy. Cancers (Basel). 2021 Aug 20;1316. DOI:10.3390/cancers13164184 [7]Arighi CN, Hartnell LM, Aguilar RC, et al. Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor...
Autophagy has been defined as a cytoplasmic protein and organelle degradation mechanism involving the lysosomal machinery in which dysfunctional, damaged and/or excess cellular components are recycled for homeostasis, survival, and the production of energy and metabolic precursors [1-5]. ...
Autophagy as a target for anticancer therapy. Nat Rev Clin Oncol. 2011;8:528. Article CAS PubMed Google Scholar Khan MZI, Tam SY, Law HKW. Autophagy-modulating long non-coding RNAs (lncRNAs) and their molecular events in cancer. Front Genet. 2018;9:750. Article Google Scholar Jiang C...
Dysregulated iron metabolism is a hallmark of many cancers, including glioblastoma (GBM). However, its role in tumor progression remains unclear. Herein, we identified coatomer protein complex subunit zeta 1 (COPZ1) as a therapeutic target candidate whic