Lactate production during exercise. In: Pernow, B., Saltin, B. eds. (1971) Muscle metabolism during exercise. Plenum, New York, pp. 401-407Hermansen, L.: Lactate production during exercise. In: Muscle metabolism during exercise. Pernow, B., Saltin, B. (eds.), pp. 401–407. New ...
The regulation of lactate production in muscle, release into the circulation and its clearance from the blood is far from being fully understood. Lactate is a very dynamic metabolic compound; unfortunately it is often merely used as a descriptive index of exercise intensity. However, those who ...
The production of lactate as fuel increases when the demand for oxygen and ATP exceeds the cellular supply, such as during strenuous exercise and infection21,22. Lactate is a classical byproduct of glucose metabolism, and the main lactate production pathway depends on glycolysis (Fig.1). The gl...
Twitter Google Share on Facebook lactate (redirected fromlactate shuttle) Thesaurus Medical Encyclopedia lac·tate1 (lăk′tāt′) intr.v.lac·tat·ed,lac·tat·ing,lac·tates To secrete or produce milk. [Latinlactāre, lactāt-, fromlac, lact-,milk; seelacto-.] ...
Lactate is known as the end product of anaerobic glycolysis, a pathway that is of key importance during high intensity exercise. Instead of being a waste product lactate is now regarded as a valuable substrate that significantly contributes to the energy production of heart, noncontracting muscles ...
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( 17 ). the fate of oral fructose administered with glucose during exercise, and more specifically the rate of lactate production elicited after fructose administration, has not been quantitatively assessed. the aim of this study was to assess the metabolic effects of ingesting equimolar amounts of...
or the oxygen supply of body tissues and cells is insufficient under conditions of intense exercise or diseases such as tumours, inflammation, infection, and ischaemia, the tca cycle is inhibited, and the aerobic glycolysis pathway is activated to compensate for the lack of atp production by ...
working skeletal muscle is not the sole source of blood lactate in humans during whole-body exercise. Epinephrine is more likely to signal glycolysis and lactate production in noncontracting tissues than in working muscle; in working muscle, epinephrine augments glycolysis, leading to increased lactate...
‘old school’ and missing significance of lactate shuttlingin vivo. Further, their proposed a mechanism is unlikely as the gut is under perfused during exercise [28] and the mechanism would be counterproductive because during exercise lactate is purposefully disposed of as a fuel energy source and...