9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook lactate (redirected fromlactates) Thesaurus Medical Encyclopedia lac·tate1 (lăk′tāt′) intr.v.lac·tat·ed,lac·tat·ing,lac·tates To secrete or produce milk. ...
Lactate production increases when the demand for ATP and oxygen exceeds supply, as occurs during intense exercise and ischaemia. The build-up of lactate in stressed muscle and ischaemic tissues has established lactate's reputation as a deleterious waste product. In this Perspective, we summarize ...
The product of anaerobic respiration is lactate or lactic acid; that’sexactlywhat is measured through the lactate test. As our muscles continue to burn while we work out and our anaerobic respiration mode is switched on, lactate will continue to build up in the muscles. If this continues, t...
The production of lactate as fuel increases when the demand for oxygen and ATP exceeds the cellular supply, such as during strenuous exercise and infection21,22. Lactate is a classical byproduct of glucose metabolism, and the main lactate production pathway depends on glycolysis (Fig.1). The gl...
aAlthough the precise mechanisms are still unclear and debatable, the lactate paradox during maximal aer-obic exercise appears to be related to reduced lactate production (rather than clearance from the blood) pos-sibly from upregulated ATP-coupling pathways decreas-ing the contribution of fast glyco...
Lactate-derived histone lactylation is involved in multiple pathological processes through transcriptional regulation. The role of lactate-derived histone lactylation in the repair of spinal cord injury (SCI) remains unclear. Here we report that overall
Pucino V, Certo M, Bulusu V, Cucchi D, Goldmann K, Pontarini E, Haas R, Smith J, Headland SE, Blighe K, Ruscica M, Humby F, Lewis MJ, Kamphorst JJ, Bombardieri M, Pitzalis C, Mauro C (2019) Lactate buildup at the site of chronic inflammation promotes disease by inducing CD4(+...
The brain has a small net lactate production at rest while during exercise it takes up lactate in proportion to the arterial concentration. This study evaluated whether cerebral oxygen availability affects the brains lactate metabolism as arterio-venous lactate differences (a-v diff) in 16 subjects...
The brain has a small net lactate production at rest while during exercise it takes up lactate in proportion to the arterial concentration. This study evaluated whether cerebral oxygen availability affects the brains lactate metabolism as arterio-venous lactate differences (a-v diff) in 16 subjects...
3 volunteers were asked to stay still for 20 min to stabilize the sensors. The recorded CA current during the stabilization phase was not used in the analysis. Next, the stationary exercise was performed for 20 min at a fixed level. After concluding the last stage of the experiment, vo...