We selected an aptamer against a fluorogenic dye called Thioflavin T (ThT). Aptamers are single-stranded DNA that can bind a specific target. We selected the ThT aptamer using graphene oxide assisted SELEX and a low-cost Open qPCR instrument. We optimize
infusion. Accordingly, we observed a marked reduction in both plasma viremia titers and cell-associated HIV-1 RNA (CA HIV-1 RNA) levels after M10 cell infusion. These data support the adoptive transfer of M10 CAR-T cells as a novel tool for developing a functional cure for HIV-1 ...