Singh M, Couto SS, Forrest WF, Lima A, Cheng JH, Molina R, Long JE, Hamilton P, McNutt A, Kasman I, Nannini MA, Reslan HB, Cao TC, Ho CC, Barck KH, Carano RA, Foreman O, Eastham-Anderson J, Jubb AM, Ferrara N, Johnson L, Anti-VEGF antibody therapy does not promote metastas...
Fig. 7: Anti-tumor effects of the KRAS(G12D) inhibitors alone and in combination with anti-PD-L1 antibody. a Nude mice injected with Panc 04.03 cells at Day 0 were later intraperitoneally injected with TH-Z827 (at 10 mg/kg or 30 mg/kg) according to the indicated dosage schedule...
antibody targeting PD-1 that blocks the activity of the PD-1 and PD-L1 immune checkpoint to overcome the OFF signal delivered to T cells. Autochthonous autochthonous mouse models for human cancers are obtained by initiating tumors in a normal cell within the intact organism. Cellular senescence ...
小鼠抗HRAS/KRAS/NRAS (MUTATED G12D)单克隆抗体 更多供应商 生工生物工程(上海)股份有限公司 联系电话: 400-821-026 产品介绍: 中文名称:小鼠抗HRAS/KRAS/NRAS (mutated G12D)单克隆抗体 英文名称:Anti-HRAS/KRAS/NRAS (mutated G12D) mouse monoclonal antibody 小鼠抗HRAS/KRAS/NRAS (MUTATED G12D)...
the KRAS G12D program, the company has several molecules in development, including TSN084, a Type II multi-kinase inhibitor; TSN222, a first in kind dual acting tumor immune agonist (DATIA®), and a platform...
Finally, inhibition of SCF using a neutralizing antibody significantly attenuated Snail-induced migration of mast cells. Together, these results elucidate how the EMT regulator Snail contributes to inflammation associated with PDAC tumors. ©2014 American Association for Cancer Research....
G12D, and Pan-Keratin in primary epithelial cells, SV40T immortalized cells, and SV40T immortalized cells transformed with KRASG12D (SV40T LV-GK; two lines, CL1 and CL2) Samples are from the same gel/blot with different IR Dye exposures depending on the secondary for the primary antibody...
THRAP4 / MED24 ANTIBODY 100 ug,PA538545,赛默飞世尔 销售价: 询价 加入购物车 PIERCE SPIN CUPS - CELLULOSE ACETATE FILTER,69702,赛默飞世尔 销售价: 询价 加入购物车 ANTI-NESTIN EA,PA523386,赛默飞世尔 销售价: 询价 加入购物车 IL-17RA ANTIBODY 100 ul,PA587597,赛默飞世尔 销售价: 询...
We tested this antibody on tissue sections and found that it did label metaplastic and dysplastic ducts in mouse pancreas and did not label normal ducts. However, even metaplastic ducts arising in Kras+/+ mice were labeled by this antibody, indicating that it is not specific to mutant KRAS (...
that a diet with low-fiber promoted lung tumor development and reduced tumor-bearing animal long-term survival in both prophylactic early disease and established late disease of murine LSL-KrasG12D lung cancer model, which displays low neoantigen burden and is refractory to anti-PD-1 antibody. ...