Conditional Knockout Cell Line Services Fragment Deleted Stable Cell Line As a leading provider of gene editing service,CRISPR/Cas9 PlatformCBis proud to offer gene knockout cell line generation service with high quality. Depending on the excellent platform and experienced scientists, our staff has su...
Cyagen Cell Line Generation Platform Advantages Efficient Smart-CRISPR Technology:Allows for multiple knock-out strategies, higher gene editing efficiency, and ensuring protein complete non-expression to the greatest extent. Superior Customer Support:VIP project specialist is available for project follow-up...
Generation of Delta F508-CFTR T84 cell lines by CRISPR/Cas9-mediated genome editing Objectives: To provide a simple method to make a stable Delta F508-CFTR-expressing T84 cell line that can be used as an efficient screening model system fo... Chung, Woo YoungSong, MyungjaePark, JinhongNamkun...
Cyagen specializes in generating knockout/transgenic mice, rats and cell line models, as well as virus packaging, vector cloning, stem cells and cell culture reagents.
In addition, we introduce the recent advances in the methodology of cell line generation with knockout or knockdown of the PrP gene. We also discuss how these cell lines have provided valuable insights into PrP functions and show future perspectives. 展开 ...
The glutamine synthetase (GS)-based Chinese hamster ovary (CHO) selection system is an attractive approach to efficiently identify suitable clones in the cell line generation process for biologics manufacture, for which GS-knockout (GS-KO) CHO cell lines are commonly used. Since genome analysis in...
Generation of a knockout mouse embryonic stem cell line using a paired CRISPR/Cas9 genome engineering tool. Methods Mol. Biol. 1341, 321-343.Wettstein, R., Bodak, M. & Ciaudo, C. 2016. Generation of a knockout mouse embryonic stem cell line using a paired CRISPR/Cas9 genome engineering...
Lab resource: Stem Cell LineGeneration of Dip2a homozygous knockout murine ES cell line IBMSe001-A-1 via CRISPR/Cas9 technology Author links open overlay panelMingze Yao a 1, Qian Yang a 1, Mengqiao Lian a 1, Pengfei Su a, Xiaogang Cui a, Tinglin Ren a, Xiedong Wang a, Changxin ...
Although Chinese hamster ovary (CHO) cells, with their unique characteristics, have become a major workhorse for the manufacture of therapeutic recombinant proteins, one of the major challenges in CHO cell line generation (CLG) is how to efficiently identify those rare, high-producing clones among ...
Gene knockouthas advanced fromRNAinterference-mediatedgene silencingto the development of a new generation of gene-editing technology, which provides broader prospects for cellularimmunotherapy. Gene knockout combined withCARorTCRtechnology reduces the occurrence ofGVHDin universal CAR-T cell technology and...