cKIT (D816V) Assay Kit 英文名称: cKIT (D816V) Assay Kit 总访问: 49 国产/进口: 进口 半年访问: 16 产地/品牌: BPS 产品类别: 其他生物试剂 规格: 96 rxns. 最后更新: 2023-11-29 货号: 79889 CAS 号: 参考报价: 7490 立即询价 电话咨询 ...
The use of allele-specific quantitative polymerase chain reaction to identify KIT D816V in the peripheral blood of adults with mastocytosis has been reported to have value in the diagnosis, assessment of disease burden and management of this disease. To examine the value of this assay in ...
KIT (V654A/D816V) (Human) Recombinant Protein, GST Tag Protein, P6511, high quality and rigorously validated in-house for Functional Study (Functional Study). KIT (V654A/D816V) (Human) Recombinant Protein, P6511 is ready to ship.
表2. 部分常见c-kit突变的药物靶点模型 部分数据展示 图7. Anti-proliferation assay of three reference compounds on the c-Kit WT (SCF1 Dependent)/BaF3 Stable Cell Line. 图8. Anti-proliferation assay of three reference compounds on the c-Kit D816V/BaF3 Stable Cell Line. 图9. Anti-proliferati...
A sensitive, specific and cost-effective assay to detect the D816V mutation in archived formalin-fixed paraffin-embedded tissues from cases of SM has been developed. 展开 关键词: Dirofilaria repens human subcutaneous periorbital tumor-like lesion ...
kinase assay using synthetic peptides revealed that c-Kit/D816V had an altered substrate specificity resembling Src and Abl tyrosine kinases. We further present evidence that, in contrast to wild-type c-Kit, Src family kinases are dispensable for c-Kit/D816V cell survival, proliferation, and ...
(Cell-free assay)V654A KIT[1] (Cell-free assay)D816V KIT[1] (Cell-free assay)点击更多 4 nM5 nM8 nM14 nM 体外研究(In Vitro) 体外研究活性 DCC-2618有效并广泛地抑制KIT原发性和耐药性突变体,如发生在外显子9、11、13、14、17和18的突变,以及发生在PDGFRA外显子12、14、18的原发性突变[3...
(D) Ba/F3 cells expressing KIT-D816V were washed three times and then serum- and cytokine-starved for 4 hours. Cells were lysed and subjected to immunoprecipitation with an anti-STAT3 antibody. Statistical analysis was performed by quantifying Western blots from three independent experiments. ...
Third, patients diagnosed with systemic mastocytosis carrying the D816V KIT mutation, which causes KIT signaling to be constitutively active, were studied. These patients had the same order of magnitude of mast cell progenitors as healthy subjects (Figure 1A-B). Thus, dysfunctional KIT signaling ...
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