[2]Heinzelmann-Schwarz VA,Jäger W.Ki-67 expression pattern and its relevance for endocrine resistance in breast cancer.Pathology.2019;51(2):127-128。 [3]Cheang MC,Chia SK,Voduc D,et al.Ki-67 index,HER2 statu...
Immunohistochemical staining for Ki-67 is used to calculate a Ki-67 proliferation index (PI) that carries prognostic and predictive information in various cancers including breast carcinomas. Studies have documented challenges for observers to reproducibly estimate the Ki-67 PI. At present, no ...
[4]Gudlaugsson E,Skaland I,Janssen EA,et al.Comparison of the effect of different techniques for measurement of Ki-67 proliferation on reproducibility and prognosis prediction accuracy in breast cancer.Histopathology.2012;61(6):1134-1144。 [5]Correlation between expression of LRP16,Ki-67 andEGF...
INTRODUCTION: Breast cancer (BC) is a malignancy with very high incidence and mortality in Africa, especially in Western Africa where more than 25 thousand deaths are registered every year. Not all BC have the same prognosis, and being able to personaliz
The proliferation marker Ki-67 is one of the most controversially discussed parameters for treatment decisions in breast cancer patients. The purpose of th
Consequently, the proliferation index (PI) influences clinical decision-making and choice of treatment in several tumour entities. This includes breast cancer where PI is used to separate luminal A and luminal B phenotypes (Leong and Zhuang, 2011), which impacts on therapy, and neuroendocrine ...
growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation....
This cohort study of patients with breast cancer investigates whether Ki-67 expression correlates with the 21-gene recurrence score (RS) and whether high
Although Ki-67 is a commonly used measure of cellular proliferation in breast cancer tissue, its utility as a biomarker for helping to guide therapy decisions has been clouded by technical and clinical questions. However, recent efforts to develop a framework for analyzing Ki-67 and data from ...
Background. Black women with breast cancer (BC) in Nigeria have higher mortality rate compared with British women. This study investigated prognostic features of cell proliferation biomarker (Ki-67) ...