Ki-67 proliferation index was shown to be a prognostic factor in PEM, but its performance has not been directly correlated with tumor grade or mitotic score. This study evaluated the potential of Ki-67 index as a surrogate of tumor grade. We also compared the predictability of mitoses and ...
In conclusion, Ki-67 index by DIA was associated with tumor grade as well as mitotic count, and its predictability for OS was comparable to that of mitotic score, thus being a potential surrogate for tumor grade. 展开 关键词: pleural epithelioid mesothelioma mesothelioma grading Ki-67 tumor ...
Tumor grade and progesterone receptor status predict 21-gene recurrence score in early stage invasive breast carcinoma. Breast Cancer Res Treat. 2018;172(3):671-677. doi:10.1007/s10549-018-4955-z PubMedGoogle ScholarCrossref 23. Makower D, Lin J, Xue X, Sparano JA...
Selecting patients with high grade tumors for preoperative investigational treatment may be further refined according to whether the patients have Ki-67 score of ≥20 and large tumor size. Cancer 1998;83:490-497. 1998 American Cancer Society. 展开 ...
Tumor grade assessment using WHO guidelines and shown by different methods is shown in Table2. The percentage of cases scored using DIA-WSI (FOV) with grade 2 was higher at 50% compared with approximately 30% for the other methods being used to score cell blocks. The main reason for the ...
This retrospective analysis evaluated the interaction between Ki-67 and histological grade and their prognostic role in different breast cancer subtypes. In total, 2,573 breast cancer patients underwent surgery, and their histological grade and Ki-67 val
(confirmed preoperatively and/or at surgery), or 1-3 positive lymph nodes with one or more of the following: grade 3 disease, tumor size ≥5 cm (on pre-operative imaging and/or at surgery), or a Ki-67 score of ≥20%) 2 years of adjuvant abemaciclib can be considered in combination...
The odds ratios for associating high Ki-67 expression (as compared to low Ki-67 expression) with cancer grade and tumor stage were; OR 1.254; 95% CI 0.586–2.683 and OR 1.374; 95% CI 0.705–2.677 respectively. On the other hand, the odds ratios for associating high BCL-2 expression (...
Tumor specimens were reexamined to confirm the diagnosis, recalculate the Ki-67 index, and assess the presence of an SGP, introducing an SGP score from 0 to 3+. The current grading system with a G1/G2 cutoff of 2% was more discriminative (HR 2.30; 95% CI 1.20-4.38, p = 0.012) ...
Distribution was significantly different across all subgroups evaluated, Ki-67 expression being significantly higher in premenopausal women P = 0.0002), and being directly associated with pT, pN, tumor grade, presence of PVI, and inversely associated with the expression of ER and PgR receptors ...