Ki-67乳腺癌新辅助化疗Neoadjuvant chemotherapy( NAC )is one of the main strategies for patients with locally advanced breast cancer. Clinical and pathologic response rates are equivalent used for evaluating therapeutic effect. The expression of Ki - 67 protein is associated with cell proliferation. It...
[11] Takada M, Sugimoto M, Masuda N, et al. Prediction of postoperative disease- free survival and brain metastasis for HER2-positive breast cancer patients treated with neo-adjuvant chemotherapy plus trastuzumab using a machine learning algorithm[J]. Breast Cancer Res Treat, 2018, 172(3): 611...
[7]“Chen, Xianyu et al. “The predictive value of Ki-67 before neoadjuvant chemotherapy for breast cancer: a systematic review and meta-analysis.” Future oncology (London, England) vol. 13,9 (2017): 843-857. doi:...
Ki-67%breast cancer subtype%chemotherapy%early-stage breast cancer%endocrine therapy%estrogen receptor-positive%gene expression assays%progesterone receptor Ki-67breast cancer subtypechemotherapyearly-stage breast cancerendocrine therapyestrogen receptor-positivegene expression assaysprogesterone receptor... Nobuyuki...
Anthracycline-containing regimens are irreplaceable in neoadjuvant chemotherapy (NAC) for breast cancer (BC) at present. However, 30% of early breast cancer (EBC) patients are resistant to anthracycline-containing chemotherapy, leading to poor prognosis and higher mortality. Ki-67 is associated with ...
结论纳入Ki-67的分子分型法能更好地区分出对新辅助化疗缺乏敏感性的乳腺癌。 关键词: 癌,导管,乳腺;抗肿瘤联合化疗方案;Ki-67抗原;治疗结果;分子分型 ABSTRACT ObjectiveTo investigate the response to neoadjuvant chemotherapy (NAC) among different molecular subtypes of breast cancers using molecular classificat...
3.NishimuraR, Osako T, Okumura Y, et al. Clinical significance of Ki-67 in neoadjuvantchemotherapy for primary breast cancer as a predictor for chemosensitivity andfor prognosis. Breast Cancer,2010,17(4):269-275 4.KlöppelG, La Rosa S. Ki67 labeling index: assessment and prognostic role in...
Ki-67 expression is correlated with cell proliferation and is a prognostic marker for various cancers; however, its function is unknown. Here we demonstrate that genetic disruption of Ki-67 in human epithelial breast and colon cancer cells depletes the cancer stem cell niche. Ki-67 null cells ...
[1] Zhu X,Chen L,Huang B,et al.The prognostic and predictive potential of Ki-67 in triple-negative breast cancer.Sci Rep 2020;10:225.DOI:10.1038/s41598-019-57094-3 [2] Golshan M,Loibl S,Wong SM,et al.Brea...
In order to define accurate survival outcome in breast cancer, 10-year follow-up is required and such long-term survival information are few and difficult to gather.We recruited 253 breast cancer patients who undertook operation with no prior chemotherapy. Ten-year survival outcomes were evaluated ...