背景:在KEYNOTE-826(NCT03635567)研究中,帕博利珠单抗(pembro)联合化疗(chemo)±贝伐珠单抗(bev)为持续性、复发或转移性宫颈癌患者提供了有统计学意义的、有临床意义的PFS和OS的改善。在目前对KEYNOTE-826的分析中,我们评估了几个关键...
Here, we present the protocol-specified final OS analysis results of KEYNOTE-826. Methods: Eligible adults with persistent, recurrent, or metastatic cervical cancer not previously treated with systemic chemo (prior radiosensitizing chemo allowed) and not amenable to curative treatment (surgery or ...
Here, we present the protocol-specified final OS analysis results of KEYNOTE- 826. Methods: Eligible adults with persistent, recurrent, or metastatic cervical cancer not previously treated with systemic chemo (prior radiosensitizing chemo allowed) and not amenable to curativ...
PFS with KEYTRUDA and ipilimumab at the protocol-specified first-interim analysis (6 months) and in a 5-year post hoc extension analysis4,6 6-Month Analysis6 PFS by BICR Analysisk KEYTRUDA 10 mg/kg IV Q3W (n=277)KEYTRUDA 10 mg/kg IV Q2W (n=279)Ipilimumab IV (n=278) ...
Protocol-Specified Final OS Analysis (Median Follow-up Time: 31.0 Months)2 Overall Survival (OS) KEYTRUDA + plat/pem (n=410)Plat/pem (n=206) HR=0.56 (95% CI, 0.46–0.69) Median OS 22.0 months(95% CI, 19.5–24.5) Median OS 10.6 months(95% CI, 8.7–13.6) Exploratory Analysis (Medi...
The iPad is a network device ..it eschews a plethora of ports in favor of technologies like Bluetooth and Wifi which enable efficient data transfer via network protocol. I'm hoping that iCloud becomes that pervasive network "glue" that ties the PC era with the Post-PC era ...
Here, we present the protocol-specified final OS analysis results of KEYNOTE-826. Methodology Eligible adults with persistent, recurrent, or metastatic cervical cancer not previously treated with systemic chemo (prior radiosensitizing chemo allowed) and not amenable to curative treatment (surgery or ...