Kanamycin sulfate is an aminoglycoside antibiotic that inhibits Gram-positive and gram-negative bacteria as well as mycoplasma. The mechanism of action is to target the binding of 70S ribosomal subunit in bacteria, thereby inhibiting ribosomal translocation and causing miscoding to further interfere with ...
Still, several TC007 properties such as the mechanism of action, BBB permeability and pharmacokinetic profile should be addressed in future experiments before advancing to clinical usage. Show moreView article Novel medicinal and synthetic chemistry strategies against antimicrobial resistance Elham Rezaee, ...
Antibiotics: Bekanamycin is primarily used as an antibiotic in the field of medicine. Its mechanism of action involves binding to the bacterial ribosome, thereby inhibiting protein synthesis. This makes it effective against a wide range of gram-negative and gram-positive bacteria. Research: Bekanam...
Its mechanism of action involves binding to the bacterial ribosome, inhibiting protein synthesis, and ultimately leading to bacterial cell death. Due to its broad-spectrum activity and effectiveness, Bekanamycin plays a crucial role in the field of infectious disease management....
mechanism of plant cell by producing ROS and causing oxidative stress; (ii) cause harm to the cellular integrity by binding oxygen, nitrogen or sulfur groups in biomolecules; (iii) replace essential metal ions from biomolecules; (iv) change the active conformation of enzymes or larger ...
It is with this in mind that we chose to explore the mechanism of action of kanamycin. We hypothesized that kanamycin does have secondary effects on E. coli in addition to the direct inhibition of protein synthesis, as previously suggested in Experiment A1a[13]. To explore the pleiotropic ...
Article: Mechanism of inhibition of translocation by kanamycin and viomycin: a comparative study with fusidic acid
Rich, and others in Bill's group in the years that followed, carried out many elegant, insightful and informative analyses of Tn5 structure, and mechanism and control of transposition.43,44 I moved from Julian's lab in April 1977 to set-up my own transposition research group in the ...
Selectable markers of bacterial origin such as the neomycin phosphotransferase type II gene, which can confer kanamycin resistance to transgenic plants, re... A Mentewab,CN Stewart 被引量: 444发表: 2005年 Mechanism of resistance to amikacin and kanamycin in Mycobacterium tuberculosis An A1400G mut...
biosynthesis.142,143It has also been reported that the introduction ofkanJandkanKgenes into a gentamicin producer strain resulted in the formation of deaminated 2′-OH-containing gentamicins.100,144 Sign in to download full-size image Fig. 19.Deamination mechanism in kanamycin A biosynthesis....