2,白山毛桃根提取物可以抑制M21细胞侵袭迁移能力及诱导M21细胞凋亡,其机制可能是通过下调与肿瘤细胞凋亡密切相关的Bcl-2/Bax的比率有关;另外,白山毛桃根提取物能抑制肿瘤M21细胞增殖可能与其下调与肿瘤细胞免疫逃逸密切相关的PD-L1,PD-L2分子蛋白的表达有关. 3,白山毛桃根提取物可以诱导K562细胞凋亡,其机制可能是...
星堡主壁窒生堂垡笙皇上海中医药大学硕士学位论文畲药白山毛桃根提取物对肿瘤细胞M21、K562增殖抑制作用及其分子机制研究ResearchontheeffectsandpotentialmechanismsoftheextractiveofRadixAcmidiaeErianthaeon‘nhibitionofproliferati inM21irlhibitionofproliteration1andK562tumorlcells研究生:王水英导师:**东专业:中西医...
胞Q链mRNA表达及细胞增殖能力的影响。 方法:将针对K562细胞的a链特异设计的、化学方法合成的siVA 以瞬时转染的方式通过脂质体Oligofectamine转染K562细胞,在转染后 24、48、72、96小时等时点上,采用实时定量逆转录聚合酶链反应(Real-time quantitativereverse ...
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