Given the twofold aim of this research, the K562 erythroleukemia cell line was chosen as a model based on some of its characteristics: it is a human, immortal cell line committed to the erythroid lineage (erythroleukemia), which is easy to culture, and has a high proliferation rate. ...
The presence of multiple lineage surface markers and cytoplasmic characteristics in leukemic cells is not indicative of lack of potential to differentiate. K562 cells cannot be compared to any normal stage of hematopoietic differentiation, but they do have the capacity to differentiate along erythroid...
Biological Characteristics of Wt1 Gene in Relation to Ph Leukemia Cell Line K562 Journal of Experimental Hematology / Zhongguo Shiyan Xueyexue ZazhiLI YanLI Xiao-YanWANG LinTIAN ZhengRAO QingJIA Hai-RongWANG Hui-JunWANG MinMI Ying-Chang
A human haemopoietic cell line (K562) which exhibits various erythroid characteristics, has been utilised as a model system for studying erythropoietic differentiation. We have analysed the alterations in expression of cell membrane determinants which accompany the induction of Hb synthesis. We confirm ...
关键词:白血病细胞;致瘤性;裸小鼠 StudyofthebiologicalcharacteristicsofhumanhightumorigenicleukemiacelllineK562——ninnudemice LUShuqing,XUXiaoping,WANGJianmin,eta1.(DepartmentofHaematology,ChanghaiHospital,theSecondary MilitaryMedicalUniversity,Shanghai200433) Abstract:ObjectiveTostudythebiologicalcharacteristicsofhuman...
Dimery IW, et al. Variation amongst K562 cell cultures. Exp. Hematol. 11: 601-610, 1983. PubMed: 6576909 Chan YJ, et al. Two distinct upstream regulatory domains containing multicopy cellular transcription factor binding sites provide basal repression and inducible enhancer characteristics to the ...
Embryonic-fetal erythroid characteristics of a human leukemic cell line We have studied a number of cell surface, enzyme, and protein markers in the human leukemic K562 cell line. We have confirmed previous observations that th... EJ Benz,MJ Murnane,BL Tonkonow,... - 《Proceedings of the Na...
Variation amongst K562 cell cultures. Exp. Hematol. 11: 601-610, 1983. PubMed: 6576909 Chan YJ, et al. Two distinct upstream regulatory domains containing multicopy cellular transcription factor binding sites provide basal repression and inducible enhancer characteristics to the immediate-early IES (...
K562celllineK562/Vp16overexpressingP—gPwasachievedbyexposureofK562cellstostepwiseincreaseof concentrationsofVpl6.Asmallsetofsidepopulation(SP)withthecharacteristicsofstemcellsbeingcapa— bleofefflUXfluorescentdyeHoeehst33342inthecelllinewasisolatedbyflowcytometry.Themechanisms ...
Variation amongst K562 cell cultures. Exp. Hematol. 11: 601-610, 1983. PubMed: 6576909 Chan YJ, et al. Two distinct upstream regulatory domains containing multicopy cellular transcription factor binding sites provide basal repression and inducible enhancer characteristics to the immediate-early IES (...