伤活性的抑制效应结果与转染了空质粒的对照组相比,外周血NK细胞对K562G1的杀伤率降低3243 (P<001)结论 靶细胞表达HLAG1分子可明显抑制NK细胞的杀伤效应: :关键词:HLAG1;NK细胞;转染 [中图分类号] R39212 [文献标识码] A ExpressionofHLA--G1antigenonK562cellinhibitscytotoxicityme-- ...
小鼠淋巴瘤细胞 Nb2-11 Cell Line from rat 小鼠T淋巴细胞 CTLL-2 霍奇金淋巴瘤细胞 Hs 611.T 人恶性非霍奇金淋巴瘤患者的自然杀伤细胞 NK92 人弥漫大 B淋巴瘤悬浮细胞 WSU-DLCL2 人急性非B非T淋巴细胞性白血病细胞 Reh 人弥漫大B淋巴瘤细胞 0CI-Ly7 人弥漫大B淋巴瘤细胞 SU-DHL-8 人B淋巴瘤细胞 Far...
反应性氮代谢物及其清除剂影响NK细胞抗K562细胞效应的实验 研究 姓名:*** 申请学位级别:硕士 专业:内科学(血液肿瘤) 指导教师:**新 20080301 ABMT Bcl.2 DD decONOO. DHT DM[EM DMSO ELISA E/T FADD FLICE FBS FITC GSH GST.S IFN.Y IL.2 IL...
K562/IL-21 cell line细胞株K562-based aAPCs with membrane-bound IL-21 (mbIL21).mbIL21-expressing aAPCs promoted log-phase NK cell expansion without evidence of senescence for up to 6 weeks of culture. Despite the significant increase in proliferation, mbIL21-expanded NK cells also showed a sig...
Effect of phenols on natural killer (NK) cell-mediated death in the K562 human leukemic cell line. Cell Biol Int 2005;29:884-9.Dedoussis, G.V.Z., Kaliora, A.C. and Andrikopoulos, N.K. (2005) Effect of Phenols on Natural Killer (NK) Cell-Me- diated Death in the K562 Human ...
NK? cell mediated cytotoxicity. We propose the possibility of using Raman spectroscopy to measure the relative expression of HLA class I molecules at the single-cell level. Raman spectra are recorded for three cell lines ?K562, T2, and T3? and monomers ?HLA class I folded, unfolded and ...
培养时间的延长,NK细胞凋亡率显著增高;在相同培养时间的情况下,随着效靶比降低,NK细胞凋亡率逐渐升高,杀伤活性逐渐减低.结论 红白血病细胞系K562可以诱导活化的NK细胞凋亡,这有可能是肿瘤细胞发生免疫逃逸的机制之一.%Objective To investigate the apoptosis of NK cells induced by the erythroleukemia cell line ...
结论:M I CA /B 在K 562和K562/AO 2细胞表达的差异与NK 细胞的杀伤活性有关;NK 细胞对K 562/AO 2细胞杀伤活性降低与HLA I 类分子无关;M IC A /B 在多药耐药肿瘤细胞的低表达导致耐药肿瘤细胞对NK 细胞杀伤敏感性下降。关键词 自然杀伤细胞;MH C I 类链相关分子A /B ;K562细胞中图分类号 R ...
1.The Effect and Molecular Mechanism for Artesunate on the CD34～+ Cell Separated from K562 Cell Line;青蒿琥酯对K562细胞系CD34～+细胞的作用及分子机制 2.Effect of Tiopronin to Reverse the ROM Mediated Inhibition of NK Cell-mediated Killing of K562 Cell in Vitro;硫普罗宁体外逆转ROM对NK细胞抗...
survivin基因的表达水平与NK细胞活性呈负相关。混合培养上清中分泌的IFN-γ,K562/survivin+组是K562组的1/4.5,是K562/survivin-组的1/8。结论高表达的survivin可以抑制淋巴细胞的增殖、NK细胞活性及IFN-γ的分泌。 References [1] 罗颖, 温贤浩, 徐酉华. K562细胞survivin基因表达对淋巴细胞增殖和功能的影响[J]....