Strung up with the revolutionary Dark Matter Damping and Titanal I-Beam construction, the Disruption 78Ti can arc like nothing you’ve ever experienced.In line with the rest of the Disruption collection, these are made for downhill charging, with maximum control and maneuverability.From the firmn...
The anterior cingulate cortex (ACC) is a brain area involved in modulating behavior associated with social interaction, disruption of which is a core feature of autism spectrum disorder (ASD). Functional brain imaging studies demonstrate abnormalities of the ACC in ASD as compared to typically develo...
13]. However, a significant amount of GRK2 was reported to be associated with internal microsomal membranes by means of electrostatic interactions between the N-terminal region of the kinase (RH domain) and an unknown protein which is an integral component of ...
The efficiency of siRNA-1 was relatively satisfying with 60% of total YAP1 without disruption of exogenous one (Fig. 5K). The trans- membrane cell of the HA-YAP1143A group declined sig- nificantly compared with the HA- YAP1143D (378 ± 79.8 VS 651.7 ± 58.1, P ...
Such accu- mulations are consistent with disruption to axonal transport of cdk5/p35. Damage to axonal transport is a major feature of Alzheimer's disease [2, 5, 9, 30, 55]. Of interest therefore were our findings that LMTK2 levels are reduced in Alzheimer's disease cortex (af- fected ...
While, originally, Bartters’ syndrome was largely attributable to the disruption of NaCl reabsorption in the thick ascending limb and resistance to loop diuretic furosemide [64,69], animal knockout models also exhibited a dramatic reduction of salt reabsorption in the distal convoluted tubule and ...
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