(2006). PEPPER, a novel K-homology domain gene, regulates vegetative and gynoecium development in Arabidopsis. Dev. Biol. 289, 346-359.Ripoll JJ, Ferra´ndiz C, Marti´nez-Laborda A, Vera A (2006) PEPPER, a novel K-homology domain gene, regulates vegetative and gynoecium development ...
Lorkovic ZJ, Barta A (2002) Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant ... Zdravko,J,Lorkovi,... - 《Nucleic Acids Research》 被引量: 558发表: 2002年 RNA recognition motif (RRM)-containing proteins in Bombyx mo...
Employing mass spectrometry and enzymatic analyses, we identified Caspase-3 as the enzyme that cleaves hnRNP K specifically.In vitrostudies revealed that cleavage by Caspase-3 at amino acids (aa) D334-G335 removes the C-terminal hnRNP K homology (KH) domain 3 that confers binding of hnRNP K...
The three-dimensional structures of target proteins in wild type and ohms1 mutant were predicted by the homology modeling method. Protein models of wild type and ohms1 mutant target genes were displayed by PyMOL Tutorial molecular 3D structure displaying software, and built in the same temple and...
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composedofthreeKHdomainsthatinduceDNA—RNAbindingandauniqueKIdomain.hnRNPK cannotonlyregulategeneexpressionthroughCT--dependentorCT--independentpathwaysinthepro·- gressoftranscription。butalsomodulatetheefficiencyofmRNAtranslationbyitsphosphorylation, indicatingitsfunctionaleffectongenetranslationregulationandintracellularsig...
hnRNPK is a conserved DNA and RNA binding ribonucleoprotein with the triple K-homology domain, which functions by regulating the transcription and post-transcriptional metabolism of RNA[22-23]. It has been reported that hnRNPK expression is augmented in a number of human cancers, including lung ...
‘recognizes’ H4K20me3 via its first bromo-adjacent-homology domain (DNMT1BAH1). Engagement of DNMT1BAH1-H4K20me3 ensures heterochromatin targeting of DNMT1 and DNA methylation at LINE-1 retrotransposons, and cooperates with the previously reported readout of histone H3 tail modifications (i....
Homology modeling The X-ray structures of the kinase domains of the high-affinity NTRK1 (TrkA, (4AOJ; Chain A) and NTRK3 (TrkC) (6KZC; Chain A) were used as the template for building the open and closed conformers of NTRK1/TrkA and NTRK3/TrkC, respectively. The open and closed...
The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain The Nova family of proteins are target antigens in the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia and contain K-homology (KH)-type RNA ... KB Jensen,K Musunuru,HA Lewis,... ...