The Rel homology domain (RHD) is an evolutionarily conserved domain found in some eukaryotic transcription factors, including NF│蔅, the nuclear factors of activated Tヽells (NFATs) and the...Springer Berlin HeidelbergEncyclopedia of Molecular Pharmacology...
迄今为止,在哺乳动物细胞内共发现5种NF-κB/Rel家族成员,它们分别是RelA(即p65)、RelB、C-Rel、p50/NF-κB1(即p50/RelA)和p52/NF-κB2。 这些成员均有一个约300个氨基酸的Rel同源结构域(Relhomology domain,RHD)。这个高度保守的结构域介导Rel蛋白形成同源或异源二聚体,该结构域也是NF-κB与靶基因DNA序列...
This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in...
This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in...
Mutant Rel-homology domain promotes transcrip- tion by p50/NFkappaB1. Oncogene 1997;14:1521-30.Xu, X. and Gelinas, C. (1997). A mutant Rel-homology domain promotes transcription by p50/NFkappaB1. Oncogene 14, 1521-1530.Xu X, Gelinas CA. mutant Rel-homology domain promotes transcription ...
Rel homology domain is placed at the N-terminal region of these proteins where it is used for NF-κB dimerization and DNA binding activity. The C-terminal region of p65, c-Rel and RelB have TAD (transcription activation domain), where they activate gene expression. p50 and p52 on the ...
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This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in...
This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in...
指标别名 REL?proto-oncogene;NF-kB subunit;C-Rel 克隆性 Monoclonal 检验物种 human 应用范围 WB,IP 基因名称 REL 抗体来源 Rabbit 抗体类型 IgG 免疫原 A synthesized peptide derived from human c-Rel c-Rel contains an amino-terminal DNA-binding domain referred to as the REL homology domain (REH) ...