T细胞介导的细胞免疫在抗肿瘤免疫与机体免疫调节中发挥重大作用,其中CD4 +、CD8 + 等亚群细胞在维持机体的免疫状态、移植耐受性以及肿瘤免疫等方面具有重要作用。 人外周血白血病T细胞,JURKAT细胞上下游产品信息 上游原料 下游产品 人外周血白血病T细胞,JURKAT细胞生产厂家 ...
英文名称:Jurkat Cells 包装信息:1000000细胞数/;2000000细胞数/ 备注:Jurkat Cells(赠送Str鉴定报告)|人急性T淋巴细胞白血病细胞 人外周血白血病T细胞,JURKAT细胞专题 人外周血白血病T细胞的研究T细胞介导的细胞免疫在抗肿瘤免疫与机体免疫调节中发挥重大作用,其中CD4 +、CD8 + 等亚群细胞在维持机体的免疫状态、移植耐受...
对Jurkat细胞CD4、CD8 及P14ARF表达的影响研究 摘要 目的构建携带靶向锌指结构转录调节因子小干扰RNA(Zinc finger andBTB domain・containingprotein 7BsiRNA,ZBTB7BsiRNA) 的重组腺病毒质粒,采用腺病毒介导ZBTB7BsiRNA沉默Jurkat细胞 中ZBTB7B的表达,检测Jurkat细胞中ZBTB7B及P14ARF基因的表达 及细胞表面分子CD4和CD8的...
The results may give a clue that Jurkat cells maybe provide an ideal cell line model for studying the regulation of RAGs in peripheral T cells. 【Keywords】 T cell activators; Jurkat cells; recombinationactivating genes; reverse transcriptase polymerase chain reaction 【摘要】目的: 研究T细胞激活剂...
Human leukemic T lymphoblastoid cells (hereinafter, Jurkat T cells) have been used to model the morphofunctional reaction of T lymphocytes to 24-h in vitro contact with relief (roughness index Ra = 2.2–2.7 μm) pure titanium substrates (12 × 12 × 1 mm 3 ) covered by a calcium ...
T细胞激活剂对Jurkat 细胞重组激活基因表达的影响 作者:邹红云,马骊,姚新生,温茜,王小宁 【关键词】 T细胞激活剂,;Jurkat细胞;重组激活基因;逆转录聚合酶链反应 【Abstract】 AIM: To investigate the effects of T cell activators on the mRNA expression of recombinationactivating genes (RAGs) in Jurkat cells....
Supporting this, Rapa, by inhibiting mTOR, decreases glycolysis and promotes the differentiation of memory CD8+ T cells and the generation of regulatory T cells both in vitro and in vivo 52, 53. Since the combined inhibition of glycolysis and mTORC1 signalling can disrupt metabolic reprogramming ...
TIM-3 is a transmembrane glycoprotein encoded by the HAVCR2 gene and it regulates T cell activation [16]. TIM-3 molecules were initially identified on terminally differentiated TH1 cells and are also found on TH17 cells, regulatory T cells, exhausted CD4+ T cells, as well as CD8+ T cells...
JM细胞是1976年从一名患有T细胞白血病的14岁男性的外周血中提取的T细胞系,建系时被标记为JM, 与Jurkat E6.1来源同一患者。JM细胞是低四倍体,具有 46 条染色体和 7.8% 多倍体的扁平模态核型。JM细胞表达T细胞受体(TCR)和CD3蛋白。它们还表达CD4和CD8共受体,这有助于将它们识别为辅助性或细胞毒性T细胞。JM细胞在...
人 T 淋巴细胞系 Jurkat 细胞最初来源于一名 14 岁 T-ALL 初次复发的男性患者。Jurkat 细胞免疫表型:CD2+、CD3+、CD4+、CD6+、CD7+、CD8-、CD19-、CD34+、TCRα/β+、 TCRγ/δ-。Jurkat 细胞是亚四倍体,细胞遗传学特点:87(78-91) 4nXX, -Y, -Y, -5, -16, -17, -22, (2)(p21)/del(2...