原代T细胞或PBMC及Jurkat T 细胞激活测试(T Cell Activation Assay) T细胞或PBMC活化测定试验确定受试品对T细胞或PBMC在细胞活化过程中的调节作用。 东大生物的方法可以评估测试品在由CD3 / CD28抗体诱导下的T细胞或PBMC 活化中的作用,测试方式包括用细胞因子的ELISA或流式细胞仪(FCM)的测定。 案例一:原代T细胞激活后...
Ras activation in Jurkat T cells following low-grade stimulation of the T-cell receptor is specific to N-Ras and occurs only on the Golgi apparatus. Mol. Cell. Biol. 24:3485-3496.Perez de Castro I., Bivona T. G., Philips M. R., Pellicer A. Ras activation in Jurkat T cells ...
Thus, capsaicin and its numerous analogs may have potential use as immunomodulatory drugs and should be further investigated in models of inflammation and T-cell activation. 展开 关键词: model fitting quantification limit censored data DOI: doi:10.1023/A:1012299115260 被引量: 72 ...
细胞名称:Jurkat-Cas9细胞 人T淋巴细胞白血病细胞Cas9稳定表达细胞系 细胞简称:Jurkat-Cas9细胞 产品货号:TCH-C225-M01 修饰基因:Cas9 修饰类型:过表达稳转 转导方法:慢病毒转染 抗性基因:Hygro 细胞鉴定:Q-PCR检测合格 种属来源:人 组织来源:外周血 疾病特征:急性T淋巴细胞白血病 细胞形态:淋巴母细...
Downregulation of SATB1 increases the invasiveness of Jurkat cell via activation of the WNT/β-catenin signaling pathway in vitro 来自 国家科技图书文献中心 喜欢 0 阅读量: 73 作者:XD Luo,SJ Yang,JN Wang,L Tan,D Liu,YY Wang,RH Zheng,XH Wu,LH Xu,H Tan ...
32922: Yang RY, et al. Expression of galectin-3 modulates T-cell growth and apoptosis. Proc. Natl. Acad. Sci. USA 93: 6737-6742, 1996. PubMed: 8692888 33013: Gibson S, et al. Functional LCK is required for optimal CD28-mediated activation of the TEC family tyrosine kinase EMT/ITK. ...
Human T-Cell Leukemia Virus Type 1 Tax Induction of NF-κB Involves Activation of the IκB Kinase α (IKKα) and IKKβ Cellular Kinases which normally phosphorylate IκBα on both of its N-terminal regulatory serines in response to tumor necrosis factor alpha (TNF-α) and interleukin-1 ....
Previous studies have shown that selenite exerts pro-apoptosis and pro-autophagy effects and is associated with the activation of ER stress in T-cell acute lymphoblastic leukemia (T-ALL). Herein we demonstrate the underlying mechanisms by which the activation of p38MAPK plays essential roles in apo...
These findings open interesting perspectives for novel combinatorial therapeutic strategies targeting metabolic checkpoints to block the proliferation of T cells.Similar content being viewed by others MYO1F regulates T-cell activation and glycolytic metabolism by promoting the acetylation of GAPDH Article ...
deBelle I, Cai S and Kohwi-Shigematsu T (1998) The genomic sequences bound to special AT-rich sequence-binding protein 1 (SATB1)in vivoin Jurkat T cells are tightly associated with the nuclear matrix at the bases of the chromatin loops.J. Cell Biol141: 335–348 ...