these the JAK-STAT pathway is one of the architecturally simplest paradigms, allowing direct communication fromtransmembrane receptors to the nucleus (Figure 1). Pioneering work on the control of gene expression by interferons led to the discovery of this pathway; however, it is now recognized that...
Cytokine Growth Factor Re2 views ,1998 ;83(4) :2052211 Progress in the Studies of JAK2STAT Signal Pathway Chen Xiao2ping ① , Xu Fei ②① Ph. D. Candidate , Lecturer , ② Undergraduate , College of Life Science , 君,已阅读到文档的结尾了呢~~ 立即下载 相似精选,再来一篇 ...
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1. Ananthakrishnan R, Hallam K, LiQ,Ramasamy R. JAK-STAT pathway in cardiac ischemic stress. Vascul Pharmacol.2005Oct 28; PubMed ID: 16260187 2. Walker JG, SMith MD. The Jak-STAT pathwayin rheumatoid arthritis. J. Rheumatol. 2005 Sep;32(9):1650-3. PubMedID:16142855 3. Marrero MB. ...
JAK/STAT信号通路的激活: 目前已知包括白细胞介素(ILs)、集落刺激因子(CSF)、激素样细胞因子和生长因子在内的近60种细胞因子通过JAK-STAT途径作为其主要的、必需的启动转录方式。 细胞因子与其相应的受体结合后,传递信号至细胞内结构域(ICD),导致酪氨酸磷酸化并激活受体相关的JAK,随后磷酸化并活化STAT。
Janus kinases (JAK); Signal transducers and activators of transcription (STAT) JAK/ STAT signaling is activated by a wide array of cytokinesand growth factors leading to the stimulation of cell...doi:10.1007/978-3-540-29807-6_242Marissa K. Caldow...
2022年10月13日,Cell期刊发表了题为“The JAK-STAT pathway at 30: Much learned, much more to do”(JAK-STAT通路的第30年: 我们已经学到了很多,但还有更多的要做)的长文综述,接下来带大家简单了解一下: 图1. 这个时间轴罗...
Jak-STAT Pathway 来自 Springer 喜欢 0 阅读量: 24 摘要: Several Jak kinases, signal transducers and activators of transcription (STATs) regulate the signal transduction of interleukins and interleukin-mediated transcription. The pathway may be activated... DOI: 10.1007/978-1-4020-6754-9_8868 ...
(2012). JAK/STAT pathway plays a critical role in the proinflammatory 55 56 57 gene expression and apoptosis of RAW264.7 cells induced by trichothecenes... J Tep,B Videmann,M Mazallon,... - 《Toxicology Letters》 被引量: 49发表: 2007年 Inflammatory cytokines regulate microRNA-155 expressio...
The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway serves as a paradigm for signal transduction from the extracellular environment to the nucleus. It plays a pivotal role in physiological functions, such as hematopoiesis