Isoform-level ribosome occupancy estimation guided by transcript abundance with Ribomap. Bioinformatics 2016;32:1880-2. https://doi.org/10.1093/bioinformatics/btw085.Wang,H., McManus,J. and Kingsford,C. (2016) Isoform-level ribosome occupancy estimation guided by transcript abundance with Ribomap. ...
isoform-level ribosome occupancy estimation guided by transcript abundance with ribomap.[2016][bioinformatics(oxford,e.isoform-level核糖体入住率评估指导下与ribom 文档格式: .pdf 文档大小: 101.74K 文档页数: 3页 顶/踩数: 0/0 收藏人数: 0
mRNA isoformFunctional analysisTumor-specificDiagnosisLast decades have witnessed the great progress in exploration of tumor transcriptome. However, most researches were restricted in gene-level expression. mRNA isoforms, especially tumor-specific isoforms have not been fully explored in tumor. Here, by ...
Unsupervised clustering of TCGA (the Cancer Genome Altas Consortium) GBM samples, based on isoform-level gene-expression profiles, recaptured the four known molecular subgroups but switched the subtype for 19% of the samples, resulting in significant (P = 0.0103) survival differences among the ...
Isoform-level Analysis of Next Generation Sequence Data Highlights Mechanisms of Ewing Sarcoma Progression 来自 Semantic Scholar 喜欢 0 阅读量: 25 作者:JN Billaud,C Bullitt,W Brasor 摘要: Ewing Sarcoma (ES) is a prototypical translocation sarcoma, which harbors characteristic translocations fusing ...
Performed 0 gene-level transcription difference tests Performed 0 CDS-level transcription difference tests Performed 0 splicing tests Performed 0 promoter preference tests Performing 0 relative CDS output tests Writing isoform-level FPKM tracking Writing TSS group-level FPKM tracking ...
More than 25% of the transcriptome exhibits differential splicing or expression, with isoform-level changes capturing the largest disease effects and genetic enrichments. Coexpression networks isolate disease-specific neuronal alterations, as well as microglial, astrocyte, and interferon-response modules ...
isoform with the highest expression in a sample (main isoform) (Fig.1d). However, from those genes with multiple isoforms expressed at the RNA level, 3,471–3,570 (52.6–55.5%) of genes in human and 577–898 (27.6–34%) in mouse had an alternative isoform translated (Fig.1d). From...
mRNA-Seq technology has revolutionized the field of transcriptomics for identification and quantification of gene transcripts not only at gene level but also at isoform level. Estimating the expression levels of transcript isoforms from mRNA-Seq data is
However, we cannot simply consider the principal isoform of each gene to be the target major isoform for a drug, because isoform-level interactions are usually rewired by tissue-specific exons, and the transcript isoform of a given gene with the highest expression level is not always the ...